Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   EL176_RS03350 Genome accession   NZ_LR134332
Coordinates   697437..699644 (-) Length   735 a.a.
NCBI ID   WP_010946363.1    Uniprot ID   Q5ZXV5
Organism   Legionella pneumophila strain NCTC11193     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 692437..704644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL176_RS03330 (NCTC11193_00657) - 692943..694871 (-) 1929 WP_011213221.1 hypothetical protein -
  EL176_RS03335 (NCTC11193_00658) - 694997..695389 (-) 393 WP_010946360.1 hypothetical protein -
  EL176_RS03340 (NCTC11193_00659) - 695526..695903 (+) 378 WP_010946361.1 hypothetical protein -
  EL176_RS03345 (NCTC11193_00660) - 696104..697411 (+) 1308 WP_011213222.1 tetratricopeptide repeat protein -
  EL176_RS03350 (NCTC11193_00661) comEC 697437..699644 (-) 2208 WP_010946363.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EL176_RS03355 (NCTC11193_00662) pilE 699722..700171 (-) 450 WP_010946364.1 type IV pilin protein Machinery gene
  EL176_RS03360 (NCTC11193_00663) - 700183..703692 (-) 3510 WP_011213223.1 pilus assembly protein -
  EL176_RS03365 (NCTC11193_00664) - 703705..704217 (-) 513 WP_010946366.1 pilus assembly protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83235.94 Da        Isoelectric Point: 9.8039

>NTDB_id=1121699 EL176_RS03350 WP_010946363.1 697437..699644(-) (comEC) [Legionella pneumophila strain NCTC11193]
MEIFCFLIGVLYAYTYNIYLTIAIPLLFYITPRYPIVLFFIAGCGFALIHQWIVSPKGMPDTQVITQAQLEGTIASIPMQ
HPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPVLRAGQRWQLSVKLKKPRNFHNPGGFNYVRYLAARHIHWTGYIRYRNN
KLISNQPPSFSWLALREKIGDALTKLAPDTETAGIIEALTLNVTHHISSDHWNLFRRTGTIHLFGISGEHIALVSGIFFI
VMRWIWSINYRCCLFLPANTIASIGGLLAALPYAFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLALQLSCLIGLMPLTLHWYSYGSINGFLANLFAIPLVSFLIVPLAL
MTMITSPFHWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSVTMMLAMTAGLFLRVLLPVKPFKHLAILWIILPL
FPPRTAIYPGEALINILDVGQGLAVAIQTQHHVLLYDTGDSYFQGSDLGQMAIIPFFRSIGIKTIDKIVISHPDKDHKGG
LNSLEKEMKVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIRESFNKKNNNSCILQVSNSAGRVLLTGDIEKAAEE
YLVRNYGSQLASEILVVPHHGSKTSSSYRFLLEVNPLYAIASLGFDNRFKFPHSKTLQSMKTLGITFFRTDECGMAAIKL
PASGKINKPTCMQAV

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=1121699 EL176_RS03350 WP_010946363.1 697437..699644(-) (comEC) [Legionella pneumophila strain NCTC11193]
ATGGAAATTTTTTGCTTTTTAATAGGCGTACTTTATGCCTATACCTATAATATTTATCTAACTATTGCGATTCCTTTACT
CTTTTATATCACACCAAGATATCCCATTGTCCTGTTCTTCATTGCCGGGTGTGGCTTTGCCCTGATTCATCAGTGGATTG
TATCTCCCAAGGGCATGCCTGATACGCAAGTAATCACACAAGCCCAATTGGAAGGAACAATTGCTTCCATCCCGATGCAA
CATCCTAACAAAACCCAATTCCATTTTGCAATTGAAAAAATTAATAATAACCCTGCTCAAGGCTTGATCCAATTAAACTG
GTATAACAAACCACCTGTCTTACGAGCCGGTCAGCGATGGCAACTTTCAGTGAAACTAAAAAAACCTCGTAACTTCCACA
ACCCGGGAGGTTTTAATTATGTACGTTACCTGGCGGCTCGTCATATCCATTGGACTGGCTATATTCGTTATCGGAATAAT
AAGCTAATTAGCAATCAACCCCCTTCTTTCAGTTGGTTAGCACTACGTGAAAAAATAGGGGATGCTTTGACAAAACTGGC
GCCGGATACAGAAACGGCAGGCATCATCGAAGCATTGACGTTAAATGTTACTCACCATATCAGTTCAGATCATTGGAATT
TGTTCCGAAGAACAGGAACGATACATTTATTCGGGATTTCAGGAGAGCACATCGCTCTGGTCTCTGGCATTTTCTTTATA
GTAATGAGATGGATTTGGTCAATAAATTATCGATGCTGTTTGTTCTTACCGGCCAATACCATAGCGAGTATCGGTGGGCT
ACTGGCCGCCTTGCCCTATGCTTTTTTAGCCGGGTTTGAGCCTCCTGTGCAACGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATAGGAAAACAACGTTTTACACCATGGCAAATATGGAGATATGCCTTATTTTTAGTCTTGTGTATTGAG
CCCCATGCCGTATTCCTGCAAGGTTTTTACTTTTCATTTCTTGCCGTGGCCTGTCTTCTATTGACTCATCAACGCTGGCC
ACTGAAAAATTATAAAAAAACACTGGCATTACAATTAAGCTGCCTCATTGGATTAATGCCCTTGACTCTCCATTGGTATT
CCTATGGTTCTATCAATGGATTTCTTGCCAATTTATTCGCCATACCTTTAGTCAGTTTTCTGATAGTACCCTTGGCTTTA
ATGACCATGATAACGAGTCCATTTCATTGGTCCTGGATATTGATGAAACCATTGGCGTGGCTTGTTGCCCTGTTACTGCA
AGGACTAACGTATGTTGAGCAAATAGCAGGGATCAATATCACCTGGTCCATCACCTCGGTAACAATGATGCTCGCTATGA
CAGCAGGTCTGTTTTTAAGGGTATTATTACCTGTCAAGCCATTCAAACACTTGGCTATCCTTTGGATTATCCTTCCCTTA
TTTCCACCTCGTACTGCAATTTATCCCGGGGAAGCATTAATTAATATTTTGGATGTTGGGCAAGGACTTGCCGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGACACGGGAGATTCCTACTTTCAGGGGAGTGATTTAGGGCAAATGGCGATAA
TCCCCTTTTTCAGGTCAATTGGAATAAAAACAATTGACAAAATAGTAATAAGCCATCCCGATAAAGATCATAAAGGCGGA
TTAAATTCCCTTGAAAAAGAGATGAAAGTCAATCAATTAATAGTGAATGATCCCTATTTTTATAAACGTGGAAGTAATTG
TCATTCATACCCGCAATGGCAATGGGATGGGGTGAGTTTTCGTTTTTTACCCATCAGGGAATCTTTCAATAAAAAAAATA
ACAATTCTTGTATCTTACAGGTAAGTAATTCGGCTGGCAGGGTTTTGTTAACGGGAGATATTGAAAAAGCAGCTGAAGAG
TACCTGGTAAGAAACTACGGCAGTCAGCTGGCATCCGAAATTTTAGTTGTGCCTCATCATGGGAGCAAAACGTCTTCATC
CTATCGATTTTTGCTGGAAGTAAACCCGCTTTATGCCATTGCATCCTTAGGATTTGATAATCGCTTCAAATTTCCACATT
CTAAAACTTTGCAAAGCATGAAAACATTAGGTATCACTTTTTTTAGAACAGACGAATGCGGAATGGCAGCAATCAAACTA
CCTGCGTCAGGTAAAATTAACAAACCAACCTGTATGCAGGCTGTATAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(21-159)

Competence protein (Competence)

(199-464)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-578)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZXV5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

100

100

1
  comEC Legionella pneumophila strain ERS1305867

96.866

99.864

0.967

Multiple sequence alignment