Detailed information NTG1121531

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: EL133_RS04305
• Genome accession: NZ_LR134323
• Coordinates: 832498..833370 (+)
• Length: 290 a.a.
• NCBI ID: WP_006739187.1
• Uniprot ID: G5KF17
• Organism: Streptococcus urinalis strain NCTC13766
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 827498..838370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL133_RS04275 (NCTC13766_00884)	-	827879..828754 (+)	876	WP_006738825.1	F0F1 ATP synthase subunit gamma	-
EL133_RS04280 (NCTC13766_00885)	atpD	828799..830205 (+)	1407	WP_006739325.1	F0F1 ATP synthase subunit beta	-
EL133_RS04285 (NCTC13766_00886)	-	830218..830634 (+)	417	WP_006739343.1	F0F1 ATP synthase subunit epsilon	-
EL133_RS04290 (NCTC13766_00887)	-	830702..830926 (+)	225	WP_006739940.1	DUF1146 family protein	-
EL133_RS04295 (NCTC13766_00888)	murA	830998..832269 (+)	1272	WP_006738429.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL133_RS04300 (NCTC13766_00889)	-	832271..832459 (+)	189	WP_006739007.1	DNA-directed RNA polymerase subunit beta	-
EL133_RS04305 (NCTC13766_00890)	endA	832498..833370 (+)	873	WP_006739187.1	DNA/RNA non-specific endonuclease	Machinery gene
EL133_RS04310 (NCTC13766_00891)	pheS	833703..834749 (+)	1047	WP_006739473.1	phenylalanine--tRNA ligase subunit alpha	-
EL133_RS04315 (NCTC13766_00892)	-	834837..835361 (+)	525	WP_006738735.1	GNAT family N-acetyltransferase	-
EL133_RS04320 (NCTC13766_00893)	pheT	835376..837781 (+)	2406	WP_006739045.1	phenylalanine--tRNA ligase subunit beta	-
EL133_RS04325 (NCTC13766_00894)	-	837839..838201 (+)	363	WP_006739685.1	OsmC family protein	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 32314.88 Da
• Isoelectric Point: 9.8245

>NTDB_id=1121531 EL133_RS04305 WP_006739187.1 832498..833370(+) (endA) [Streptococcus urinalis strain NCTC13766]
MAFNKKQQKSIISLIVVIVSVIFIVLSNGNTNSNNSTLTQILSSYLGFNQSHYKQNNSSSQEDTPSQALAESVLTSSVKQ
SLGKNIKWNGYGAFIINNNQTDLNASVSSQPYAENKTKVVNHQIVPTVANALLSRATRQYRNRYETESRRSNWKPAGWHQ
VYNLKGEYDHAVDRGHLIGYALVGNLKGFDASMTNVNNIATQLAWANQSNNRYSTGQNYYESMVRRALDSNKRVRYRVTL
IYDGDNILSSGSHIEAKSDDGSLEFNVFVPNVQPGLSVDYATGYIKANHS

Nucleotide

• Length: 873 bp

>NTDB_id=1121531 EL133_RS04305 WP_006739187.1 832498..833370(+) (endA) [Streptococcus urinalis strain NCTC13766]
ATGGCTTTTAATAAAAAACAACAAAAATCTATCATATCATTAATTGTTGTTATCGTTTCAGTAATTTTTATTGTCTTATC
AAATGGTAACACCAATTCTAATAACTCAACTTTAACACAAATCTTATCATCTTATTTAGGTTTTAATCAGAGTCATTACA
AACAAAATAATTCTTCAAGTCAAGAAGATACTCCAAGTCAAGCATTAGCTGAATCTGTCTTAACTAGCTCTGTTAAGCAA
TCACTTGGTAAAAACATTAAATGGAATGGCTATGGAGCATTTATTATTAATAATAATCAAACAGACTTGAATGCAAGTGT
TTCAAGTCAACCTTATGCAGAAAACAAAACAAAAGTTGTTAATCATCAGATTGTCCCAACTGTTGCCAATGCATTACTTT
CAAGAGCGACAAGACAATACAGAAATCGTTATGAAACAGAATCAAGACGAAGTAACTGGAAACCTGCAGGTTGGCATCAG
GTTTATAACTTAAAAGGAGAATATGATCATGCTGTAGATAGAGGTCATCTCATAGGTTATGCACTTGTTGGAAATCTAAA
AGGATTTGATGCTTCTATGACAAATGTTAATAATATTGCAACACAACTAGCTTGGGCAAACCAATCAAATAATCGCTATT
CAACTGGTCAAAATTATTACGAAAGTATGGTTAGACGAGCACTTGATAGCAACAAACGAGTTCGTTACAGAGTGACTTTA
ATTTATGATGGCGATAATATATTGTCAAGTGGCTCTCATATAGAAGCTAAATCAGATGATGGTTCTTTGGAATTTAATGT
GTTTGTTCCAAATGTTCAACCCGGTCTATCGGTTGATTACGCAACTGGTTACATTAAAGCTAATCATTCTTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (111-247)

3D structure

• AlphaFold DB: G5KF17

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.625	77.241	0.507
endA	Streptococcus pneumoniae D39	65.625	77.241	0.507
endA	Streptococcus pneumoniae R6	65.625	77.241	0.507
endA	Streptococcus pneumoniae TIGR4	65.625	77.241	0.507