Detailed information NTG1121445

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: EL130_RS08925
• Genome accession: NZ_LR134320
• Coordinates: 1783864..1784745 (-)
• Length: 293 a.a.
• NCBI ID: WP_126475543.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NCTC10832
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1778864..1789745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL130_RS08900 (NCTC10832_01743)	vicR	1779758..1780465 (-)	708	WP_002262930.1	response regulator YycF	Regulator
EL130_RS08905 (NCTC10832_01744)	-	1780818..1781600 (+)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
EL130_RS08910 (NCTC10832_01745)	-	1781597..1782409 (+)	813	WP_002277521.1	transporter substrate-binding domain-containing protein	-
EL130_RS08915 (NCTC10832_01746)	-	1782427..1783131 (+)	705	WP_002262933.1	amino acid ABC transporter permease	-
EL130_RS08920 (NCTC10832_01747)	-	1783146..1783796 (+)	651	WP_002262934.1	amino acid ABC transporter permease	-
EL130_RS08925 (NCTC10832_01748)	endA	1783864..1784745 (-)	882	WP_126475543.1	DNA/RNA non-specific endonuclease	Machinery gene
EL130_RS08930 (NCTC10832_01749)	-	1784787..1784975 (-)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
EL130_RS08935 (NCTC10832_01750)	murA	1784978..1786249 (-)	1272	WP_002273074.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL130_RS08940 (NCTC10832_01751)	-	1786315..1786548 (-)	234	WP_002285829.1	DUF1146 family protein	-
EL130_RS08945 (NCTC10832_01752)	-	1786821..1787237 (-)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
EL130_RS08950 (NCTC10832_01753)	atpD	1787251..1788657 (-)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
EL130_RS08955 (NCTC10832_01754)	-	1788683..1789561 (-)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32160.79 Da
• Isoelectric Point: 9.6655

>NTDB_id=1121445 EL130_RS08925 WP_126475543.1 1783864..1784745(-) (endA) [Streptococcus mutans strain NCTC10832]
MTRKTNKSKRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVSGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=1121445 EL130_RS08925 WP_126475543.1 1783864..1784745(-) (endA) [Streptococcus mutans strain NCTC10832]
ATGACTAGAAAAACGAACAAGTCTAAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TAGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	63.675	79.863	0.509
endA	Streptococcus pneumoniae D39	63.675	79.863	0.509
endA	Streptococcus pneumoniae R6	63.675	79.863	0.509
endA	Streptococcus pneumoniae TIGR4	63.675	79.863	0.509