Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   EL130_RS08315 Genome accession   NZ_LR134320
Coordinates   1646079..1646972 (+) Length   297 a.a.
NCBI ID   WP_002272311.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1641079..1651972
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS10395 (NCTC10832_01601) - 1643042..1643170 (-) 129 WP_002262718.1 hypothetical protein -
  EL130_RS10360 - 1643205..1643435 (-) 231 WP_002282891.1 hypothetical protein -
  EL130_RS08305 (NCTC10832_01602) gbpC 1643565..1645316 (-) 1752 WP_002271472.1 glucan-binding protein GbpC -
  EL130_RS08310 (NCTC10832_01603) - 1645479..1645763 (-) 285 WP_002278032.1 helix-turn-helix transcriptional regulator -
  EL130_RS08315 (NCTC10832_01604) irvR 1646079..1646972 (+) 894 WP_002272311.1 LexA family transcriptional regulator IrvR Regulator
  EL130_RS08320 (NCTC10832_01626) - 1648697..1649074 (-) 378 WP_002269450.1 type II toxin-antitoxin system HicB family antitoxin -
  EL130_RS08325 (NCTC10832_01627) - 1649092..1649283 (-) 192 WP_002265423.1 type II toxin-antitoxin system HicA family toxin -
  EL130_RS08330 (NCTC10832_01628) csn2 1649380..1650042 (-) 663 WP_002263546.1 type II-A CRISPR-associated protein Csn2 -
  EL130_RS08335 (NCTC10832_01629) cas2 1650032..1650376 (-) 345 WP_002264918.1 CRISPR-associated endonuclease Cas2 -
  EL130_RS08340 (NCTC10832_01630) cas1 1650373..1651239 (-) 867 WP_002264919.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33625.32 Da        Isoelectric Point: 6.7036

>NTDB_id=1121441 EL130_RS08315 WP_002272311.1 1646079..1646972(+) (irvR) [Streptococcus mutans strain NCTC10832]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=1121441 EL130_RS08315 WP_002272311.1 1646079..1646972(+) (irvR) [Streptococcus mutans strain NCTC10832]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCCACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTATTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAGGAACAAGATGAAACAGCAAGCTTATCTGCCAGTGATGAAACGACTGATGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(22-70)

Peptidase S24-like (Peptidase_S24)

(184-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

99.327

100

0.993

Multiple sequence alignment