Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   EL136_RS08570 Genome accession   NZ_LR134317
Coordinates   1809365..1811806 (-) Length   813 a.a.
NCBI ID   WP_042669843.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1804365..1816806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS08530 (NCTC6180_01747) groES 1804414..1804701 (-) 288 WP_012514806.1 co-chaperone GroES -
  EL136_RS08535 (NCTC6180_01748) - 1805001..1805291 (-) 291 WP_111689780.1 hypothetical protein -
  EL136_RS08540 (NCTC6180_01749) - 1805272..1805664 (-) 393 WP_043052249.1 hypothetical protein -
  EL136_RS08545 (NCTC6180_01750) - 1805646..1806959 (-) 1314 WP_154804217.1 hypothetical protein -
  EL136_RS08550 (NCTC6180_01751) - 1806962..1807375 (-) 414 WP_042669846.1 hypothetical protein -
  EL136_RS08555 (NCTC6180_01753) - 1807594..1808025 (-) 432 WP_042669845.1 hypothetical protein -
  EL136_RS08560 (NCTC6180_01755) - 1808160..1808591 (-) 432 WP_111689777.1 hypothetical protein -
  EL136_RS11355 - 1808872..1809017 (+) 146 Protein_1707 putative holin-like toxin -
  EL136_RS08570 (NCTC6180_01758) clpC 1809365..1811806 (-) 2442 WP_042669843.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  EL136_RS08575 (NCTC6180_01759) - 1811806..1812267 (-) 462 WP_012514800.1 CtsR family transcriptional regulator -
  EL136_RS08580 (NCTC6180_01760) - 1812439..1812642 (-) 204 WP_012514799.1 cold-shock protein -
  EL136_RS08585 (NCTC6180_01761) - 1813021..1813728 (-) 708 WP_111677660.1 exotoxin beta-grasp domain-containing protein -
  EL136_RS08595 (NCTC6180_01763) ahpC 1814353..1814913 (+) 561 WP_012514798.1 alkyl hydroperoxide reductase subunit C -
  EL136_RS08600 (NCTC6180_01764) ahpF 1814934..1816466 (+) 1533 WP_138118663.1 alkyl hydroperoxide reductase subunit F -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90394.26 Da        Isoelectric Point: 6.4367

>NTDB_id=1121287 EL136_RS08570 WP_042669843.1 1809365..1811806(-) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIKAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICKVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLRDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AIHTAVKLAQRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSRLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLK
IGVSRGKLAFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1121287 EL136_RS08570 WP_042669843.1 1809365..1811806(-) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
GTGATGATTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAAGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCATATTTTATTAGCTATGGTAGCTGTTGACCATTCCTTAGCGGCCATGGTGTTAAGCGAATTTGAACGAA
AGATTAAGGCCGAAGAGTATGAGGCTGCTGCTATTTTAGCCATGGGAAAAAGTCCCAAAGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTAAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTGCTTTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTCTGTTAGAACTAGCGGGCTACAGGC
TCAGAGATTCTGGCAAAGGAGAGCCTCGCTTTGCAGATTTGCGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGTAAGATCATTTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACACTTGATGCCGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAAC
TCAAGAGGAATATCAAAAGCACATTGAAAAGGACGCAGCTCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTATCCATACTGCTGTGAAGCTGGCTCAGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACACCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCGGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAGGCTATCAGGTATTCCACTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
AAATTTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ATCAGTCAGGCATTCGCACAGGCAGACGCCCGATTGGCTCCTTTATGTTTCTTGGTCCAACCGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCTCGTCTCAATGGTGCTCCTCCTGGCTATGTTGGCTATGATGAAGGAGGCGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTCGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCGGTCATGACCATCAAGCAATGGAAA
AGCGTATTTTAGAGGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAAAAGGTGGTCTTCCACAGC
CTAACACAGGAAAACATGCGTGATGTGGTCAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTGTCTGAAGCTGGTTACGATGTTGAAATGGGGGCTCGCCCACTTCGTC
GCACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGAGTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGTTAGCTTTTGATATTGCTTGA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(374-457)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-51)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(94-131)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

74.293

100

0.743
  clpC Streptococcus thermophilus LMD-9

72.181

100

0.724
  clpC Streptococcus thermophilus LMG 18311

71.936

100

0.722
  clpC Streptococcus pneumoniae Rx1

65.848

100

0.659
  clpC Streptococcus pneumoniae D39

65.848

100

0.659
  clpC Streptococcus pneumoniae TIGR4

65.725

100

0.658
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.862

100

0.502
  clpC Bacillus subtilis subsp. subtilis str. 168

43.976

100

0.449
  clpE Streptococcus mutans UA159

45.666

79.459

0.363

Multiple sequence alignment