Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   EL143_RS11400 Genome accession   NZ_LR134313
Coordinates   2409349..2411580 (-) Length   743 a.a.
NCBI ID   WP_126326787.1    Uniprot ID   A0A448DB73
Organism   Neisseria canis strain NCTC10296     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 2404349..2416580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL143_RS11390 (NCTC10296_02291) modA 2405008..2405757 (-) 750 WP_085416213.1 molybdate ABC transporter substrate-binding protein -
  EL143_RS11395 (NCTC10296_02292) - 2406055..2409216 (-) 3162 WP_085416214.1 Ig-like domain-containing protein -
  EL143_RS11400 (NCTC10296_02293) comA 2409349..2411580 (-) 2232 WP_126326787.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EL143_RS11405 (NCTC10296_02294) - 2411682..2412557 (-) 876 WP_085416215.1 hypothetical protein -
  EL143_RS11410 (NCTC10296_02295) - 2412806..2413219 (-) 414 WP_085416216.1 hypothetical protein -
  EL143_RS11415 (NCTC10296_02296) ybaK 2413247..2413729 (-) 483 WP_085416217.1 Cys-tRNA(Pro) deacylase -
  EL143_RS11420 (NCTC10296_02297) - 2413806..2414162 (+) 357 WP_085416218.1 RidA family protein -
  EL143_RS11425 (NCTC10296_02298) - 2414237..2414848 (-) 612 WP_085416219.1 glutathione S-transferase family protein -
  EL143_RS11430 (NCTC10296_02299) pdxA 2415242..2416228 (+) 987 WP_085416220.1 4-hydroxythreonine-4-phosphate dehydrogenase PdxA -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 81088.89 Da        Isoelectric Point: 10.3050

>NTDB_id=1121109 EL143_RS11400 WP_126326787.1 2409349..2411580(-) (comA) [Neisseria canis strain NCTC10296]
MYRIERCLPAWVLGVAASFALPAVPAWYVTAAAGTGLLLVARRSGVAVVLLAALLGMAYGIWRTELALANQWPVGRFAAD
TLTLKVTGLPQREERRVRFEAQVQDAGGRQRRVQLSDYSLRDWPVGSVWRANVRLRAPVGEVNLRGFNREAWALANGLDA
LGTVGKAREQVGQDPAGGVLGLRVAISGNWQQVQGFEQGVALMRALSIGEQGALPNRAWQAFRPLGLTHLVSISGLHVSM
VGLMAAWLARLVLRRLPFSFKRPRTVVLAAGLAAACLYALLAGFGVPTQRTVLMLAAFAWIWHSRKGQSVWFAWWAALSA
VLLFDPLAVLGVGTWLSFGLVAALLWISAWRLEEKGWRVFWRGQYALLLVSLVALGFMFAALPLISPLVNLLAVPWFSWV
LVPLALAASAFPFIPLQTFAAGAGQYTMHALFWLGDRAPEWSVAAAPAGLLWLAAAAVSAALLPRGMGLRPWAFIVLAGF
VFYRPPAVPHGAVKITVWDVGQGLAVSFHTASKTLLFDTGTEAAAQTQLIPSLRAMGVRRLDAAVFSHHDNDHDGGAELI
RQAFSPTVVWAGQPGFYPNARPCHEGKAWNWDGVHFEWLSLSEKSDDDNEQSCILRVVAAEKALLVTGDLSRRGEQSLVG
QYGEDLYSHVLVLGHHGSNSASSSAFLNVVAPQYAIASSGFANAYGHPAEAVKNRLRAHGIRLMRTDLHGVQQFWFVKKE
ERSSDLEPDSSKPYWQKKPFKHE

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=1121109 EL143_RS11400 WP_126326787.1 2409349..2411580(-) (comA) [Neisseria canis strain NCTC10296]
GTGTACCGAATCGAACGCTGTCTGCCCGCATGGGTGTTGGGAGTTGCGGCTTCTTTTGCGTTGCCGGCCGTGCCTGCATG
GTATGTAACGGCTGCTGCAGGCACGGGTTTGCTGCTGGTTGCGCGGCGCAGCGGTGTGGCTGTTGTGCTGTTGGCGGCGT
TGTTGGGTATGGCATACGGTATCTGGCGCACTGAGCTTGCTTTGGCAAACCAATGGCCTGTCGGGCGGTTTGCGGCAGAT
ACGCTAACGTTGAAAGTAACCGGCCTGCCTCAGCGGGAAGAGCGGCGGGTAAGGTTTGAAGCGCAAGTGCAGGATGCGGG
CGGGCGGCAACGGCGGGTTCAGCTTTCCGATTATTCGTTGCGGGATTGGCCTGTGGGCAGTGTGTGGCGGGCTAATGTGA
GGCTGCGGGCGCCGGTGGGCGAGGTGAACCTGCGCGGTTTCAATCGGGAAGCGTGGGCGTTGGCCAATGGTTTGGATGCT
TTGGGCACGGTCGGGAAGGCGCGCGAACAGGTCGGGCAGGATCCTGCGGGCGGTGTGCTTGGGCTGCGTGTGGCAATCAG
CGGCAATTGGCAGCAGGTGCAGGGTTTCGAGCAAGGCGTGGCGCTGATGCGTGCTTTGAGCATAGGCGAGCAAGGTGCGC
TGCCGAACCGGGCTTGGCAGGCGTTCCGCCCTTTGGGCTTGACCCACTTGGTCAGCATATCCGGCCTGCATGTCAGTATG
GTGGGTTTGATGGCGGCATGGTTGGCGCGGTTGGTGCTGCGCCGGCTGCCGTTTTCGTTTAAAAGGCCGCGCACGGTGGT
GTTGGCGGCCGGTTTGGCGGCTGCGTGTCTTTATGCGCTGCTGGCAGGGTTCGGCGTGCCGACGCAGCGCACTGTATTGA
TGCTGGCTGCATTTGCTTGGATTTGGCATTCGAGAAAAGGGCAGTCCGTTTGGTTTGCCTGGTGGGCGGCGCTCTCGGCC
GTGTTGCTGTTTGACCCTCTGGCGGTGTTGGGTGTGGGCACTTGGCTTTCGTTCGGTTTGGTGGCCGCTTTATTGTGGAT
AAGCGCTTGGCGGTTGGAAGAAAAAGGGTGGCGGGTGTTTTGGCGCGGTCAGTATGCCTTGCTGCTGGTGTCTTTAGTGG
CTCTGGGGTTTATGTTTGCCGCTTTGCCTTTAATCAGCCCGCTGGTAAATTTGCTCGCCGTGCCTTGGTTTTCGTGGGTG
TTGGTGCCGTTGGCGTTGGCGGCATCCGCATTTCCTTTCATTCCTTTGCAAACTTTCGCGGCCGGTGCAGGTCAATACAC
GATGCATGCCTTGTTCTGGCTGGGCGACCGGGCGCCGGAATGGAGCGTTGCCGCAGCGCCTGCGGGCTTGTTGTGGTTGG
CGGCGGCAGCTGTATCGGCAGCGTTGTTGCCGCGCGGGATGGGGCTGAGGCCGTGGGCGTTTATCGTGTTGGCCGGTTTC
GTTTTTTACCGCCCGCCTGCCGTGCCGCATGGTGCTGTAAAGATTACGGTGTGGGATGTCGGGCAGGGGCTGGCCGTCAG
CTTTCACACCGCTTCCAAAACGCTGCTGTTCGATACCGGAACGGAAGCTGCGGCGCAAACGCAGCTGATTCCGAGCCTGC
GTGCAATGGGTGTGCGCAGGCTGGATGCCGCGGTATTTTCCCATCACGATAACGACCACGACGGCGGAGCCGAACTTATC
AGACAGGCATTCAGCCCGACAGTGGTATGGGCGGGTCAGCCCGGATTTTATCCGAATGCACGGCCTTGCCATGAGGGCAA
AGCTTGGAACTGGGACGGCGTGCATTTCGAATGGCTAAGCCTGTCTGAAAAATCAGATGACGATAACGAACAAAGCTGTA
TTTTGCGTGTGGTGGCGGCTGAAAAAGCGTTGCTGGTTACGGGCGATTTGAGCCGGCGGGGCGAGCAGTCGTTGGTCGGG
CAATATGGCGAAGACTTGTACAGCCATGTGTTGGTACTCGGCCATCACGGCAGCAACAGCGCGTCTTCAAGCGCATTTTT
GAATGTGGTTGCGCCGCAATATGCCATAGCGTCCAGCGGTTTTGCCAACGCTTACGGGCATCCTGCCGAAGCGGTGAAAA
ACCGCTTGCGCGCGCACGGTATCCGACTGATGCGCACGGATTTGCATGGTGTACAACAATTCTGGTTTGTGAAAAAAGAA
GAGAGGTCTTCCGATTTGGAGCCGGATTCAAGCAAACCGTATTGGCAGAAAAAGCCGTTTAAGCATGAATAA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(509-677)

Competence protein (Competence)

(206-462)

Domain of unknown function (DUF4131) (DUF4131)

(9-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448DB73

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

57.375

99.462

0.571

Multiple sequence alignment