Detailed information NTG1120865

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EL115_RS00690
• Genome accession: NZ_LR134307
• Coordinates: 125801..128230 (+)
• Length: 809 a.a.
• NCBI ID: WP_126441068.1
• Uniprot ID: -
• Organism: Streptococcus milleri strain NCTC10708
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 120801..133230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL115_RS00660 (NCTC10708_00128)	-	121308..122093 (+)	786	WP_070668576.1	hypothetical protein	-
EL115_RS00670 (NCTC10708_00130)	rpsB	122740..123522 (+)	783	WP_126441066.1	30S ribosomal protein S2	-
EL115_RS00675 (NCTC10708_00131)	tsf	123605..124648 (+)	1044	WP_126441067.1	translation elongation factor Ts	-
EL115_RS00680 (NCTC10708_00132)	-	124725..125075 (-)	351	WP_003071086.1	hypothetical protein	-
EL115_RS00685 (NCTC10708_00133)	-	125336..125797 (+)	462	WP_037597472.1	CtsR family transcriptional regulator	-
EL115_RS00690 (NCTC10708_00134)	clpC	125801..128230 (+)	2430	WP_126441068.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
EL115_RS00695 (NCTC10708_00135)	-	128277..128717 (+)	441	WP_119055658.1	GNAT family N-acetyltransferase	-
EL115_RS00700 (NCTC10708_00136)	dusB	128788..129759 (-)	972	WP_172594011.1	tRNA dihydrouridine synthase DusB	-
EL115_RS00705 (NCTC10708_00137)	hslO	129746..130618 (-)	873	WP_331852736.1	Hsp33 family molecular chaperone HslO	-
EL115_RS00710 (NCTC10708_00138)	-	130826..132097 (-)	1272	WP_003077837.1	toxic anion resistance protein	-
EL115_RS00715 (NCTC10708_00139)	-	132116..132934 (-)	819	WP_126441071.1	hypothetical protein	-

Sequence

Protein

• Length: 809 a.a.
• Molecular weight: 89954.25 Da
• Isoelectric Point: 6.4081

>NTDB_id=1120865 EL115_RS00690 WP_126441068.1 125801..128230(+) (clpC) [Streptococcus milleri strain NCTC10708]
MKHSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGAFTIWPF
SYRMKVLFLTAEQIAEAVHAKNLGTEHVLLAMLFDRGSLAARILEFIGFSYEDKEGALRMTDLRKNLEHKASWNKEDLKA
IRHLNKNAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPVIGRDKEISRMLQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKYIEKDAALSRRFAKVAIEEPTVADSIAILQGLKKTYEDHHKVVITDSAIET
AVKYAHRYLTSKHLPDSAIDLLDEAAATVQNKGPQNHVKVELSAADEALMAGNWNKVSTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVHFDHESMEKRMMEELKKSYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKVGVK
AGKLKFEVL

Nucleotide

• Length: 2430 bp

>NTDB_id=1120865 EL115_RS00690 WP_126441068.1 125801..128230(+) (clpC) [Streptococcus milleri strain NCTC10708]
ATGAAACATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGTTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTATCCACTTGAAA
TTGATGATTTTGAAAAGGCGGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGCTTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGTTATTTTTGACTGCTGAACAAATTGCAGAGGCGGTTCATGCCAAGAACCTTGGGACAGAGCA
TGTGTTGCTAGCTATGTTATTTGACCGAGGAAGTTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGTGCTCTACGCATGACAGATCTTCGGAAAAATTTAGAGCATAAGGCAAGCTGGAATAAAGAGGATTTAAAGGCG
ATTCGTCACCTAAATAAAAATGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGGTCATTGGGCGGGATAAAG
AGATTTCTCGCATGCTTCAGATTTTAAGTCGCAAGACGAAAAATAATCCAGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCCCTTGGTTTGGCGCAACGTGTGGCAGCTGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGACATGTCATTCTTTTCATTGATGAGCTTCATACTATTATGGGGTCGGGTAGCGGGATTGACTCGACA
TTAGATGCAGCGAACATTCTCAAGCCAGCTTTGGCCAGAGGGACACTCAGAACGGTCGGCGCAACGACACAAGAAGAGTA
CCAGAAATATATTGAAAAGGACGCAGCTCTTTCACGGCGCTTTGCTAAGGTTGCTATTGAAGAGCCAACAGTAGCTGATA
GTATTGCGATTTTACAAGGGCTAAAGAAAACTTATGAAGATCACCACAAGGTCGTGATTACGGATTCGGCCATTGAGACG
GCTGTTAAGTATGCTCATCGTTATCTAACAAGCAAACATCTACCGGATTCGGCCATTGATTTGCTAGATGAAGCCGCTGC
AACAGTACAAAATAAAGGTCCGCAAAATCACGTAAAAGTCGAATTGAGTGCAGCAGACGAGGCTTTAATGGCAGGCAATT
GGAACAAAGTTAGTACGTTGTTGGAGAAAGAGAGTCAGCCGATTGTCTATAAATTAAGAGTGAAAGACGAGGATGTTTTG
GCAACGCTCAGCAGTTTATCAGGTATTCCCGTGCAAAAGTTGACGCAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAACTGCACAAGCGGGTCATTGGGCAAAATGAAGCAATTTCTGCTATTAGTCGAGCGATTAGGCGCAATCAATCTGGTA
TCCGCACTAGCAAGCGTCCAATTGGCTCCTTTATGTTCTTAGGGCCAACCGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCACTGATTCGTTTTGATATGAGTGAATACATGGAAAAATTTGCTGCCAG
TCGCCTCAATGGAGCGCCTCCAGGTTATGTTGGTTATGAAGAAGGGGGCGAATTGACTGAAAAAGTTCGCAATCGTCCGT
ACTCTGTGCTCCTCTTTGATGAGGTAGAAAAAGCTCATCCTGATATTTTCAATGTGCTTCTCCAAGTCTTAGATGACGGG
GTGCTGACAGACAGCAAGGGGCGTAAGGTGGATTTTTCCAATACCATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTGCGGGACGACAAGACGGTTGGTTTTGGAGCAAGAGATGTTCACTTTGATCATGAAAGCATGGAAAAACGTATGATGG
AAGAGCTCAAGAAAAGTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTGGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
GCCGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGTCCATTGCGTCGAATTCTACAAA
CTCGGGTGGAAGACCATTTATCAGAATTACTTTTAGCAGGTGAGCTAAAAACGGGACAAAGCTTGAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (231-347)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (717-797)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-60)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (91-134)

• AAA lid domain (AAA_lid_9) (371-441)

• AAA domain (Cdc48 subfamily) (AAA_2) (539-710)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	77.189	100	0.774
clpC	Streptococcus pneumoniae Rx1	77.189	100	0.774
clpC	Streptococcus pneumoniae D39	77.189	100	0.774
clpC	Streptococcus mutans UA159	66.135	100	0.666
clpC	Streptococcus thermophilus LMG 18311	65.356	100	0.658
clpC	Streptococcus thermophilus LMD-9	65.233	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.759	100	0.511
clpC	Bacillus subtilis subsp. subtilis str. 168	45.318	99.011	0.449