Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EL119_RS09400 Genome accession   NZ_LR134305
Coordinates   1776429..1777145 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain NCTC1803     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1771429..1782145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL119_RS09370 (NCTC1803_01775) - 1771676..1772302 (+) 627 WP_000522380.1 nitroreductase family protein -
  EL119_RS09375 (NCTC1803_01776) - 1772631..1773416 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  EL119_RS09380 hld 1774015..1774095 (-) 81 WP_000046023.1 delta-hemolysin -
  EL119_RS09385 (NCTC1803_01778) agrB 1774386..1774955 (+) 570 WP_001105714.1 accessory gene regulator AgrB -
  EL119_RS09390 (NCTC1803_01779) agrD 1774952..1775092 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  EL119_RS09395 (NCTC1803_01780) agrC 1775117..1776410 (+) 1294 Protein_1748 quorum-sensing sensor histidine kinase AgrC -
  EL119_RS09400 (NCTC1803_01781) agrA 1776429..1777145 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  EL119_RS09405 - 1777217..1777324 (+) 108 WP_041204320.1 hypothetical protein -
  EL119_RS09410 (NCTC1803_01782) - 1777512..1778471 (-) 960 WP_001253306.1 carbohydrate kinase family protein -
  EL119_RS09415 (NCTC1803_01783) - 1778468..1779952 (-) 1485 WP_000141421.1 sucrose-6-phosphate hydrolase -
  EL119_RS09420 (NCTC1803_01784) - 1780101..1781051 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1120834 EL119_RS09400 WP_000688492.1 1776429..1777145(+) (agrA) [Staphylococcus aureus strain NCTC1803]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1120834 EL119_RS09400 WP_000688492.1 1776429..1777145(+) (agrA) [Staphylococcus aureus strain NCTC1803]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCC
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment