Detailed information NTG1120833

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL119_RS08880
• Genome accession: NZ_LR134305
• Coordinates: 1682523..1683566 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCTC1803
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1677523..1688566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL119_RS08850 (NCTC1803_01681)	-	1677944..1679200 (-)	1257	WP_001793428.1	aminopeptidase	-
EL119_RS08855 (NCTC1803_01682)	-	1679203..1679403 (-)	201	WP_000180462.1	DUF1128 family protein	-
EL119_RS08860 (NCTC1803_01683)	-	1679550..1680014 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
EL119_RS08865 (NCTC1803_01684)	-	1680021..1680296 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
EL119_RS08870 (NCTC1803_01685)	-	1680574..1681791 (+)	1218	WP_000037094.1	YihY/virulence factor BrkB family protein	-
EL119_RS08875 (NCTC1803_01686)	vraR	1681904..1682533 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
EL119_RS08880 (NCTC1803_01687)	vraS	1682523..1683566 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
EL119_RS08885 (NCTC1803_01688)	liaF	1683563..1684264 (-)	702	WP_126498396.1	cell wall-active antibiotics response protein LiaF	-
EL119_RS08890 (NCTC1803_01689)	-	1684279..1684665 (-)	387	WP_001110180.1	hypothetical protein	-
EL119_RS08895 (NCTC1803_01690)	map	1684882..1685640 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
EL119_RS08910 (NCTC1803_01691)	-	1686111..1687097 (+)	987	WP_000999713.1	FUSC family protein	-
EL119_RS08915 (NCTC1803_01692)	-	1687286..1687699 (-)	414	WP_014532664.1	hypothetical protein	-
EL119_RS08920	-	1687728..1687840 (-)	113	Protein_1656	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1120833 EL119_RS08880 WP_001017131.1 1682523..1683566(-) (vraS) [Staphylococcus aureus strain NCTC1803]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1120833 EL119_RS08880 WP_001017131.1 1682523..1683566(-) (vraS) [Staphylococcus aureus strain NCTC1803]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1