Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EL116_RS10140 Genome accession   NZ_LR134304
Coordinates   2050297..2051013 (+) Length   238 a.a.
NCBI ID   WP_047450206.1    Uniprot ID   A0A2K4AJ42
Organism   Staphylococcus schweitzeri strain NCTC13712     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2045297..2056013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL116_RS10110 (NCTC13712_01969) - 2045563..2046189 (+) 627 WP_047550540.1 nitroreductase family protein -
  EL116_RS10115 (NCTC13712_01970) - 2046290..2047075 (+) 786 WP_047550543.1 carbon-nitrogen family hydrolase -
  EL116_RS13990 hld 2047907..2047987 (-) 81 WP_000046022.1 delta-hemolysin -
  EL116_RS10125 (NCTC13712_01972) - 2048256..2048819 (+) 564 WP_047550546.1 accessory gene regulator AgrB -
  EL116_RS10130 (NCTC13712_01973) agrD 2048821..2048961 (+) 141 WP_047427315.1 cyclic lactone autoinducer peptide AgrD -
  EL116_RS10135 (NCTC13712_01974) agrC 2048986..2050278 (+) 1293 WP_047427312.1 quorum-sensing sensor histidine kinase AgrC -
  EL116_RS10140 (NCTC13712_01975) agrA 2050297..2051013 (+) 717 WP_047450206.1 quorum-sensing response regulator AgrA Regulator
  EL116_RS10145 (NCTC13712_01976) - 2051365..2052324 (-) 960 WP_047531772.1 carbohydrate kinase family protein -
  EL116_RS10150 (NCTC13712_01977) - 2052321..2053805 (-) 1485 WP_047550549.1 sucrose-6-phosphate hydrolase -
  EL116_RS10155 (NCTC13712_01978) - 2053956..2054906 (-) 951 WP_047531768.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27922.88 Da        Isoelectric Point: 5.8625

>NTDB_id=1120794 EL116_RS10140 WP_047450206.1 2050297..2051013(+) (agrA) [Staphylococcus schweitzeri strain NCTC13712]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDDPYEVLEQSKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1120794 EL116_RS10140 WP_047450206.1 2050297..2051013(+) (agrA) [Staphylococcus schweitzeri strain NCTC13712]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATGATCCTTATGAGGTGCTTGAGCAATCTAAAAATATGAATGACATAG
GTTGTTACTTTTTAGATATTCAACTTTCAACAGACATTAATGGTATTAAGTTAGGTAGTGAAATACGTAAGCATGACCCT
GTTGGTAATATTATATTTGTTACTAGTCATAGTGAACTTACTTATTTAACATTTGTCTACAAAGTTGCAGCAATGGATTT
TATTTTTAAAGATGATCCTGCTGAATTGAGAACTCGAATTATAGATTGTCTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATACGATGATATTATG
TTTTTCGAATCATCAACCAAATCGCATAGACTCATCGCCCATTTAGATAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAATTGAGTCAATTAGATGATCGTTTTTTCAGATGTCATAATAGTTTTGTTGTCAATCGTCATAATATCGAATCCATTG
ATTCGAAAGAACGAATTGTCTATTTTAAAAATAAAGAACATTGTTATGCATCGGTAAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K4AJ42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment