Detailed information NTG0112057

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HPYLSS1_RS01335
• Genome accession: NZ_CP009259
• Coordinates: 262738..265308 (+)
• Length: 856 a.a.
• NCBI ID: WP_077231763.1
• Uniprot ID: -
• Organism: Helicobacter pylori SS1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 257738..270308

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPYLSS1_RS01310 (HPYLSS1_00248)	xseA	257968..259230 (+)	1263	WP_077231761.1	exodeoxyribonuclease VII large subunit	-
HPYLSS1_RS01315 (HPYLSS1_00249)	-	259249..260403 (-)	1155	WP_162272628.1	DNA methyltransferase	-
HPYLSS1_RS01320 (HPYLSS1_00250)	-	260414..261028 (-)	615	WP_077231762.1	hypothetical protein	-
HPYLSS1_RS08190 (HPYLSS1_00251)	-	261215..261910 (+)	696	Protein_243	BsaWI family type II restriction enzyme	-
HPYLSS1_RS01330 (HPYLSS1_00252)	-	261907..262665 (+)	759	Protein_244	DNA-methyltransferase	-
HPYLSS1_RS01335 (HPYLSS1_00253)	clpC	262738..265308 (+)	2571	WP_077231763.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
HPYLSS1_RS01340 (HPYLSS1_00254)	-	265366..266085 (+)	720	WP_001883587.1	cytochrome c biogenesis protein CcdA	-
HPYLSS1_RS01345 (HPYLSS1_00255)	-	266095..267231 (+)	1137	WP_077231764.1	amidohydrolase family protein	-
HPYLSS1_RS01350 (HPYLSS1_00256)	mqnF	267216..268445 (+)	1230	WP_077231765.1	aminofutalosine deaminase family hydrolase	-
HPYLSS1_RS01355 (HPYLSS1_00257)	-	268505..268747 (+)	243	WP_000780061.1	nuclease	-
HPYLSS1_RS01360 (HPYLSS1_00258)	miaB	268757..270070 (+)	1314	WP_077231766.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96515.44 Da
• Isoelectric Point: 6.2213

>NTDB_id=112057 HPYLSS1_RS01335 WP_077231763.1 262738..265308(+) (clpC) [Helicobacter pylori SS1]
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHMLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELNKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMSLFESVLKPYLDTKELQKTLESLRKGATIQNKNDDSNLESLE
KFGIDLTQKALENKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPALARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMEKQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMESLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQHKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKAIKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYMEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDGKGVRVDFKNTILILTSNV
ASGALLEEDLSEADKQKAVKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENIQKKALERGINITLDEKAKEL
IAEVGFDRFYGARPLKRALYEMVEDKLAELILEDKVKENDSVAFVVENNEIVPKIK

Nucleotide

• Length: 2571 bp

>NTDB_id=112057 HPYLSS1_RS01335 WP_077231763.1 262738..265308(+) (clpC) [Helicobacter pylori SS1]
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAGGCTTTAGACAGCGCGCTCGCTTTAGCTTTACACCATAAAAA
CGCTGAAGTAACGCCCCTGCACATGCTTTTTGCCATGCTTAATAACTCCCAAGGCATTCTCATTCAAGCCTTACAAAAAA
TGCCTGTGGATATTGAAGCTTTAAAACTTAGCGTTCAAAGCGAGTTGAATAAATTTGCTAAAGTTTCACAAATCAGCAAG
CAAAATATCCAATTAAACCAAGCTTTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAAGGGGCGATTCTTT
CATCGCTACAGATGTGTATCTTTTGGCGAATATGAGCCTTTTTGAAAGCGTCTTAAAACCTTATTTAGACACTAAGGAAT
TGCAAAAAACTTTAGAATCTTTAAGAAAAGGCGCGACTATCCAAAATAAAAACGATGATTCTAATTTGGAAAGTTTGGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCTTAGAAAATAAGCTGGATCCCGTGATCGGGAGGGATGAAGAAATCATTCG
CATGATGCAAATTTTGATCAGAAAAACAAAAAATAACCCTATTTTATTAGGCGAGCCTGGAGTGGGGAAAACGGCTGTTG
TGGAAGGGTTAGCCCAACGCATTGTGAATAAGGAAGTGCCTAAAACGCTTTTAAACAAACGGGTTATCGCTTTAGATTTG
AGCTTATTGGTGGCTGGGGCGAAATACAGAGGCGAGTTTGAAGAGCGCCTAAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATCGTGGGGGCTGGGGCTAGTGAGGGGGGCATGGATGCGGCGA
ATATTTTAAAACCCGCGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTCTAAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCACTACAAAGGCGTTTCCAACCCATTTTACTCAATGAGCCTAGCATCAATGAAGCTTTACAGATTTT
AAGGGGGTTAAAAGAAACTTTAGAAACGCACCATAATATCACTATCAATGACTCCGCGCTCATAGCGAGCGCCAAACTCT
CTAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGGGCGGCTCAATTAAAAATG
CAAATGGAATCAGAGCCGGCCAAACTCTCCAGCGTTAAACGCTCCATCCAAAGATTGGAAATGGAAAAACAAGCCCTTGA
GATGGAAAAAAAAGAGAGTAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATCTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAAAACGAAAAAGAAGTGTTTAAAGAAATTTCACGCTTGAAAATGGAAATGGAAAGCTTGAAA
AAAGAGGCTGAGAGGTTTAAACGCAATGGGGATTACCAGCAAGCGGGTGAAATTGAATATTCTAAAATCCCTGAAAACAA
AAAGAAAGAAGAAGAATTGCAGCATAAATGGGAAGCGATGCAACAAAACGGGGCGTTATTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCATATCCCGGTCCAAAAAATGCTCCAAAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGGGTGGTGGGGCAAGAAAAAGCGATCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCCGGGCTTAGCGATAGCAACAAGCCCATAGGGAGTTTTCTCTTTTTAGGGCCAACAGGCGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATACGAATTGACATGAGCGAATATATGGAAAAG
CATGCCATAAGCCGTCTTATCGGGGCCGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAGTTGACTGAAGCGGTGCG
CAGAAAGCCTTATAGCGTGGTGTTATTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAACCTCTTGTTACAGGTTT
TAGATGAGGGGCATTTGACTGATGGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGTGCGCTTTTAGAAGAGGATTTGAGTGAAGCCGACAAACAAAAGGCGGTTAAAGAGAGCTTGAGGCAATTTTT
CAAGCCGGAATTTTTAAACCGCTTAGATGAAATCATCTCCTTTAACGCCCTAGATAGTCATGCTATCATTAATATCGTGG
GGATACTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGGGGTATTAATATAACCCTAGACGAAAAGGCAAAAGAATTG
ATTGCCGAAGTGGGATTTGACAGATTCTATGGCGCTAGACCCTTAAAGCGCGCGCTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAAGATAAAGTTAAAGAGAATGACAGCGTGGCATTTGTGGTAGAAAATAACGAGATTGTGCCTA
AGATTAAGTGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (201-316)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-142)

• AAA lid domain (AAA_lid_9) (339-440)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.07	100	0.439
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.45	100	0.428
clpE	Streptococcus mutans UA159	44.302	82.009	0.363