Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   EL096_RS02300 Genome accession   NZ_LR134294
Coordinates   432218..434029 (+) Length   603 a.a.
NCBI ID   WP_114880829.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC12977     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 427218..439029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL096_RS02280 (NCTC12977_00440) rnr 427513..429867 (+) 2355 WP_054387412.1 ribonuclease R -
  EL096_RS02285 (NCTC12977_00441) smpB 429830..430297 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  EL096_RS02290 (NCTC12977_00442) tehB 430313..431173 (+) 861 WP_054387413.1 SAM-dependent methyltransferase TehB -
  EL096_RS02295 (NCTC12977_00443) coiA 431246..432199 (+) 954 WP_000495909.1 competence protein CoiA Machinery gene
  EL096_RS02300 (NCTC12977_00444) pepF 432218..434029 (+) 1812 WP_114880829.1 oligoendopeptidase F Regulator
  EL096_RS02305 (NCTC12977_00445) - 434031..434744 (+) 714 WP_000230399.1 O-methyltransferase -
  EL096_RS02310 (NCTC12977_00446) prsA 434811..435752 (+) 942 WP_000727935.1 peptidylprolyl isomerase PrsA -
  EL096_RS02315 (NCTC12977_00447) - 435869..436249 (-) 381 Protein_441 transposase -
  EL096_RS02325 - 436662..436757 (+) 96 Protein_442 IS630 family transposase -
  EL096_RS02330 (NCTC12977_00449) - 437010..437630 (-) 621 WP_000780813.1 histidine phosphatase family protein -
  EL096_RS02335 (NCTC12977_00450) - 437630..438112 (-) 483 WP_001085888.1 aminoacyl-tRNA deacylase -
  EL096_RS02340 (NCTC12977_00451) - 438112..438954 (-) 843 WP_000954122.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 603 a.a.        Molecular weight: 70224.20 Da        Isoelectric Point: 4.5513

>NTDB_id=1120535 EL096_RS02300 WP_114880829.1 432218..434029(+) (pepF) [Streptococcus pneumoniae strain NCTC12977]
MVLQRNEINEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHM
KNDQDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLKGKDHVLSQREEELL
AGAGEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNV
KVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQE
ALKKAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYT
RETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLT
SDFLNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSD
YPLNVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1812 bp        

>NTDB_id=1120535 EL096_RS02300 WP_114880829.1 432218..434029(+) (pepF) [Streptococcus pneumoniae strain NCTC12977]
ATGGTATTACAAAGAAATGAAATAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCA
GGCTTGGGAAGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTG
CGGATAACCTACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATG
AAGAATGACCAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCA
AGCCTTTTCATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGC
TGCAGGTTTATCAACACTATTTTGACAAGCTCTTGAAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTG
GCTGGAGCTGGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGT
CCTAGACGATGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTC
GCCGTGGTGCCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTT
AAGGTGCAAAATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGA
AAGTGTTTATGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAA
TCTTGGGGATTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAA
GCCTTGAAAAAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTCAGCGAGCG
TTGGATTGATGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGC
TTCTCAACTGGCAAGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACT
CGTGAAACTCAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTT
GACGGAGAAATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTG
GAACAGTTTTCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACA
AGCGATTTCCTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCA
ATACGAGTGGGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAG
CCTTGGCTGAAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGAC
TATCCACTTAATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGA
ACGCCGTTTAAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(115-184)

Peptidase family M3 (Peptidase_M3)

(205-584)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.742

97.678

0.662

Multiple sequence alignment