Detailed information NTG1120350

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL092_RS03280
• Genome accession: NZ_LR134291
• Coordinates: 696940..697983 (+)
• Length: 347 a.a.
• NCBI ID: WP_012000130.1
• Uniprot ID: A8AVZ5
• Organism: Streptococcus gordonii strain NCTC7868
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 691940..702983

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL092_RS03245 (NCTC7868_00644)	-	692479..692772 (-)	294	WP_012000123.1	DUF5960 family protein	-
EL092_RS03250 (NCTC7868_00645)	-	692750..693124 (-)	375	WP_012000124.1	hypothetical protein	-
EL092_RS03255 (NCTC7868_00646)	-	693121..694536 (-)	1416	WP_012000125.1	Y-family DNA polymerase	-
EL092_RS03260 (NCTC7868_00647)	-	694540..695217 (-)	678	WP_012000126.1	helix-turn-helix domain-containing protein	-
EL092_RS03265 (NCTC7868_00648)	-	695360..695848 (+)	489	WP_012000127.1	YcxB family protein	-
EL092_RS03270 (NCTC7868_00649)	rsmD	695921..696469 (+)	549	WP_172601498.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL092_RS03275 (NCTC7868_00650)	coaD	696459..696953 (+)	495	WP_012000129.1	pantetheine-phosphate adenylyltransferase	-
EL092_RS03280 (NCTC7868_00651)	sepM	696940..697983 (+)	1044	WP_012000130.1	SepM family pheromone-processing serine protease	Regulator
EL092_RS03285 (NCTC7868_00652)	-	698155..698691 (+)	537	WP_012000131.1	YutD family protein	-
EL092_RS03290 (NCTC7868_00653)	rlmN	698701..699789 (+)	1089	WP_012000132.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL092_RS03295 (NCTC7868_00654)	-	699776..700315 (+)	540	WP_012000133.1	VanZ family protein	-
EL092_RS03300	trpB	700681..701862 (+)	1182	WP_002907062.1	tryptophan synthase subunit beta	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38051.60 Da
• Isoelectric Point: 6.1221

>NTDB_id=1120350 EL092_RS03280 WP_012000130.1 696940..697983(+) (sepM) [Streptococcus gordonii strain NCTC7868]
MRKISVYKWPIIIFSSLILLVVSLTVPLPYYIEVPGGAEDIRKVLLVDNKEDKEAGAYEFVTVGVQRATFAHLVYAWLTD
FTDIYSAEEMTGGSSDQEFIRINQFYMETSQNMAKYQGLKTAGKDISMKYLGVYVLQVAKDSTFKGILNIADTVTGVNDK
TFDSSEELVKYVNSQKLGDKVKVTYQEDGQEKSATGKIIKLENGKNGIGISLIDRTEVTSNIPIEFTTEGIGGPSAGLMF
SLSIYTQLADPTLRDGRVIAGTGSINRDGEVGDIGGIDKKVVSAAKSGASIFFAPNNPVTKEMKKIDPKAKTNYETAVEA
AKKIKTDMKIVPVKTLQDAIDYLKNNK

Nucleotide

• Length: 1044 bp

>NTDB_id=1120350 EL092_RS03280 WP_012000130.1 696940..697983(+) (sepM) [Streptococcus gordonii strain NCTC7868]
ATGAGAAAAATTAGTGTTTATAAATGGCCCATTATCATTTTTTCAAGCTTGATTTTGCTTGTCGTATCTTTGACGGTTCC
TTTACCATACTATATTGAAGTTCCTGGCGGTGCAGAGGATATTCGAAAGGTCTTGCTGGTTGATAATAAGGAAGATAAGG
AAGCTGGGGCTTACGAGTTTGTGACAGTTGGAGTTCAACGAGCAACCTTTGCTCATCTTGTCTATGCGTGGCTGACTGAT
TTCACGGATATCTACTCTGCTGAAGAAATGACTGGTGGATCATCGGACCAAGAATTTATTCGAATCAATCAGTTTTATAT
GGAAACATCCCAAAACATGGCCAAGTATCAAGGTTTGAAAACGGCTGGAAAAGATATTAGCATGAAATATCTGGGCGTCT
ATGTTTTGCAAGTCGCAAAAGATTCGACTTTTAAGGGAATTTTGAATATTGCGGACACGGTAACGGGAGTTAATGACAAG
ACTTTTGACAGTTCAGAAGAATTGGTGAAATATGTTAATTCGCAGAAATTAGGAGATAAGGTTAAGGTCACTTACCAAGA
AGATGGACAAGAAAAATCTGCTACTGGAAAGATTATTAAGCTAGAAAATGGTAAAAACGGAATTGGTATTAGCTTAATTG
ATAGAACAGAAGTTACTAGTAACATTCCAATTGAATTTACTACAGAAGGCATTGGAGGACCTAGTGCGGGTCTCATGTTT
AGCTTGTCAATCTATACACAACTTGCAGATCCAACCTTACGAGATGGACGTGTGATTGCAGGTACCGGAAGTATCAATCG
TGATGGAGAAGTTGGTGATATTGGAGGGATTGATAAGAAAGTCGTCTCAGCTGCTAAAAGTGGTGCCAGCATCTTCTTTG
CTCCCAATAATCCTGTAACAAAAGAAATGAAAAAAATCGATCCAAAAGCAAAGACAAACTATGAAACTGCAGTTGAGGCT
GCTAAAAAGATTAAAACAGATATGAAAATTGTTCCTGTTAAAACCTTACAGGATGCCATTGATTATCTTAAGAACAATAA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A8AVZ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.983	99.712	0.608