Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   EL111_RS07405 Genome accession   NZ_LR134287
Coordinates   1587298..1589577 (+) Length   759 a.a.
NCBI ID   WP_123795829.1    Uniprot ID   A0A5P3MPG3
Organism   Neisseria animalis strain NCTC10212     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1582298..1594577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL111_RS07385 (NCTC10212_01531) - 1583120..1583620 (+) 501 WP_123795836.1 CvpA family protein -
  EL111_RS07390 (NCTC10212_01532) purF 1583755..1585290 (+) 1536 WP_123795834.1 amidophosphoribosyltransferase -
  EL111_RS07395 (NCTC10212_01533) - 1585507..1586328 (-) 822 WP_123795833.1 alpha/beta hydrolase -
  EL111_RS07400 (NCTC10212_01534) - 1586438..1587235 (+) 798 WP_123795831.1 Cof-type HAD-IIB family hydrolase -
  EL111_RS07405 (NCTC10212_01535) comA 1587298..1589577 (+) 2280 WP_123795829.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 759 a.a.        Molecular weight: 83571.87 Da        Isoelectric Point: 10.3584

>NTDB_id=1120219 EL111_RS07405 WP_123795829.1 1587298..1589577(+) (comA) [Neisseria animalis strain NCTC10212]
MNPNRPFSIPATLLRFILPCWVIGVVLSFALPAIPHWAVWPSAFALLAAAGLRWRTAWLLLVLLLGTGYGVWRTENALSA
QWPLHRSEAAELTIEVADIPRINEKRVQFTATARHSSGQTFTLLLSDYQLRDWAVGSRWQVSARVRPVIGEVNLRGFNRE
TWALANGIGGVGTIGKVRQPLADGSRANLTALRETVSRRWQHTPEYGHDFADGIALMRALSIGEQSALRPELWQAFRPLG
LTHLVSISGLHVTMIALMAGWLVKQFLRRLPFTPAKPRLWILFGGLSAALLYAGMAGFGVPTQRSILMLAAFAWTWWRSR
TSSVWAGWWQALAAVLLLDPLSVLGVGTWLSFGLVAALIWGSSGRLQIRGLQTALRGQWAASVCSIVLLGHLFAALPLIS
PIINAIAIPWFSWVLTPLALSASALPFTPLQWTAAALAEYTLRFLLWLAAYAPEWPVAAAPLPLTLFAAAASLLILLPRG
LGLRPLAWLVLAAFVFYRPEKVETGRLQITVMDSGQGLSVLLQTARRTLLFDTATLPTAVSNIIPTLNALGIRRLDALVL
SHHDNDHDGGFAAVQQYTQPATLWAGQPEYYPNAQPCRRQQWQWDNVWFEFLTLPAHDNQADNDQSCILRAVAGGEAILL
TGDLAKKGELALLEQYGSKLYSQVLILGHHGSNSASSGTFLNTVSPQYAVASSGYGNAYGHPTPAVQTRVSAHGITLLRT
DQSGALRFELGSGEPYRGRLQKHKFYWQKKPFDYYSRIK

Nucleotide


Download         Length: 2280 bp        

>NTDB_id=1120219 EL111_RS07405 WP_123795829.1 1587298..1589577(+) (comA) [Neisseria animalis strain NCTC10212]
ATGAATCCAAACCGTCCGTTTTCCATACCCGCAACCCTGCTCCGCTTCATATTGCCGTGCTGGGTAATCGGCGTGGTGCT
TTCTTTCGCGCTTCCCGCCATACCGCATTGGGCGGTATGGCCGTCTGCATTTGCCCTGTTGGCGGCGGCAGGATTGCGGT
GGCGCACGGCGTGGCTGCTGCTTGTCCTGCTGCTCGGCACGGGCTACGGCGTATGGCGTACCGAAAATGCCCTCTCTGCC
CAATGGCCGCTGCACCGCTCGGAGGCGGCCGAGCTGACCATCGAAGTTGCCGACATTCCCCGCATCAATGAAAAACGGGT
TCAATTTACCGCCACTGCCCGCCATTCTTCCGGACAAACATTCACCCTGCTGCTTTCAGACTACCAACTGCGCGACTGGG
CAGTCGGCAGCCGCTGGCAGGTTTCCGCGCGGGTACGTCCCGTAATCGGAGAAGTCAACCTGCGCGGTTTCAACCGCGAA
ACATGGGCGCTGGCAAACGGTATCGGCGGCGTGGGAACGATCGGCAAAGTCCGCCAACCGCTGGCAGACGGCAGCCGCGC
AAACCTTACCGCCCTCAGGGAAACCGTCAGCCGCCGCTGGCAGCATACTCCCGAGTACGGTCATGATTTTGCAGACGGCA
TTGCCCTGATGCGCGCCTTAAGCATAGGCGAACAATCCGCCCTGCGCCCCGAATTGTGGCAGGCGTTCCGTCCTTTGGGG
CTGACACATCTGGTCAGCATTTCGGGGCTGCACGTTACCATGATTGCGCTGATGGCAGGCTGGCTGGTCAAACAATTCTT
GCGCCGCCTGCCCTTTACCCCTGCCAAACCCCGCCTGTGGATACTGTTCGGCGGCTTAAGCGCTGCGCTGCTTTACGCGG
GCATGGCGGGATTCGGCGTACCGACCCAACGCAGCATACTGATGCTGGCCGCCTTTGCTTGGACATGGTGGCGCAGCCGT
ACATCATCAGTATGGGCAGGCTGGTGGCAGGCACTCGCCGCCGTGTTATTACTCGATCCCCTTTCCGTATTGGGCGTAGG
AACTTGGCTGTCGTTCGGTTTGGTTGCCGCCTTAATTTGGGGCAGCTCGGGCCGTCTGCAAATACGCGGTTTGCAGACGG
CCTTGCGCGGGCAATGGGCGGCTTCGGTATGCTCCATCGTCTTACTCGGCCATCTGTTTGCCGCCCTGCCCTTAATCAGC
CCGATAATCAACGCCATCGCCATTCCGTGGTTTTCATGGGTGTTAACCCCTTTGGCATTATCCGCTTCCGCTCTACCGTT
TACCCCCTTGCAATGGACGGCGGCAGCCTTGGCAGAATATACCCTGCGCTTTTTATTATGGCTTGCCGCATACGCCCCCG
AATGGCCGGTTGCCGCCGCCCCGCTGCCGCTTACCCTGTTTGCAGCCGCTGCTTCCCTACTAATCCTGTTACCTCGCGGC
TTGGGTTTGCGCCCGCTGGCATGGCTGGTGCTGGCCGCCTTTGTCTTTTACCGCCCCGAAAAAGTCGAAACAGGCCGTCT
GCAAATCACCGTTATGGATTCAGGCCAAGGCTTATCCGTATTACTCCAAACCGCCCGCCGCACTCTGCTGTTCGATACCG
CCACCCTTCCTACCGCCGTTTCCAACATCATTCCCACCTTAAATGCCCTCGGCATACGCCGCTTGGACGCACTCGTCCTC
TCCCATCACGACAACGACCACGATGGCGGTTTTGCCGCCGTACAACAATACACGCAACCGGCAACCCTCTGGGCAGGCCA
ACCCGAATACTATCCCAACGCGCAACCGTGCCGCCGCCAACAATGGCAATGGGACAACGTATGGTTTGAATTTCTTACCC
TGCCCGCACACGACAACCAAGCAGACAACGACCAAAGCTGCATCTTACGCGCAGTTGCCGGCGGAGAAGCTATTTTACTG
ACCGGCGATTTGGCCAAAAAAGGCGAGCTGGCCTTGCTCGAGCAATACGGCAGCAAACTGTACAGCCAAGTGTTAATATT
GGGGCACCACGGCAGCAACAGCGCATCTTCAGGAACTTTTCTCAACACCGTTTCACCGCAATATGCCGTTGCCTCCAGCG
GCTACGGCAATGCCTACGGACACCCGACACCCGCCGTACAAACCCGCGTCAGCGCACACGGCATTACTCTGCTCCGCACC
GACCAATCCGGCGCGTTGCGGTTTGAACTCGGCAGCGGCGAACCCTATCGGGGCCGTCTGCAAAAACACAAGTTTTACTG
GCAGAAAAAACCATTCGATTACTATAGTCGAATAAAATAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(20-178)

Competence protein (Competence)

(220-477)

Metallo-beta-lactamase superfamily (Lactamase_B)

(515-584)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5P3MPG3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

62.923

97.365

0.613

Multiple sequence alignment