Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EL079_RS04335 Genome accession   NZ_LR134283
Coordinates   880120..880965 (-) Length   281 a.a.
NCBI ID   WP_018543446.1    Uniprot ID   A0A448AHX9
Organism   Streptococcus anginosus strain NCTC10713     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 875120..885965
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL079_RS04325 (NCTC10713_00908) - 876315..878084 (-) 1770 WP_003030463.1 ABC transporter ATP-binding protein -
  EL079_RS04330 (NCTC10713_00909) - 878094..879830 (-) 1737 WP_003030487.1 ABC transporter ATP-binding protein -
  EL079_RS04335 (NCTC10713_00910) endA 880120..880965 (-) 846 WP_018543446.1 DNA/RNA non-specific endonuclease Machinery gene
  EL079_RS04340 (NCTC10713_00911) - 881066..881242 (-) 177 WP_003030460.1 DNA-directed RNA polymerase subunit beta -
  EL079_RS04345 (NCTC10713_00912) murA 881235..882515 (-) 1281 WP_003030496.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EL079_RS04350 - 882554..882784 (-) 231 WP_018543445.1 DUF1146 family protein -
  EL079_RS04355 (NCTC10713_00913) - 882889..883308 (-) 420 WP_003028068.1 F0F1 ATP synthase subunit epsilon -
  EL079_RS04360 (NCTC10713_00914) atpD 883319..884725 (-) 1407 WP_003030503.1 F0F1 ATP synthase subunit beta -
  EL079_RS04365 (NCTC10713_00915) - 884760..885638 (-) 879 WP_003030484.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30803.54 Da        Isoelectric Point: 10.2989

>NTDB_id=1120021 EL079_RS04335 WP_018543446.1 880120..880965(-) (endA) [Streptococcus anginosus strain NCTC10713]
MARKKSNQKVTQSVAGLVIALVLVLGGYSFSNHHSSTKPSDSTAINRSIRTNHAAPSQELAQSVLTESVKRQLKGKIEWN
GAGAFIINENQTTLDAKVASVPYADNKTKLVRGQTVPTVANALLSKATRQYKNREETGNGSTIWTPAGWHQVKHLSGEYN
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANTSYSTGQNFYETKIRKALDKNKRVRYRVTLIYANEQDLV
PVGSHIEGKSNDDNLEINVFVPNVQTGIRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=1120021 EL079_RS04335 WP_018543446.1 880120..880965(-) (endA) [Streptococcus anginosus strain NCTC10713]
ATGGCGAGAAAGAAATCCAACCAGAAAGTAACACAAAGTGTAGCTGGTCTGGTTATAGCACTGGTTCTTGTGCTAGGAGG
TTATTCTTTTAGCAATCATCATAGTAGTACGAAGCCTTCTGACAGCACTGCTATTAATCGAAGTATTCGGACGAATCATG
CAGCACCCAGTCAAGAATTAGCACAGAGTGTTTTGACAGAATCCGTTAAACGGCAGCTCAAAGGAAAGATTGAATGGAAT
GGAGCGGGAGCTTTTATAATCAACGAAAATCAAACAACATTGGATGCCAAAGTTGCAAGCGTTCCTTACGCGGATAATAA
GACCAAGCTTGTTCGAGGTCAGACTGTTCCGACTGTAGCCAATGCTCTTTTATCCAAAGCCACTCGTCAGTATAAGAATC
GTGAGGAGACAGGAAATGGCTCCACGATTTGGACACCTGCTGGTTGGCATCAGGTGAAGCATTTATCAGGTGAATACAAT
CATGCGGTTGACCGTGGGCATTTGTTGGGTTATGCTTTGATTGGCAACTTGAAAGGCTTTGATGCTTCGACCAGCAACCC
GAAAAACATCGCTGTGCAAACAGCTTGGGCTAATCAAGCCAATACTAGTTATTCTACAGGTCAAAATTTTTATGAAACAA
AGATACGTAAGGCACTAGACAAAAATAAACGAGTTCGGTATCGGGTGACTTTGATTTATGCCAATGAACAGGATTTGGTG
CCGGTTGGTTCGCATATTGAAGGCAAATCTAATGACGACAATCTGGAAATAAATGTCTTTGTCCCCAACGTACAGACAGG
AATTCGATTAAATTATCAGACAGGAGAAGTGACCGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(84-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448AHX9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

76.549

80.427

0.616
  endA Streptococcus pneumoniae D39

76.549

80.427

0.616
  endA Streptococcus pneumoniae R6

76.549

80.427

0.616
  endA Streptococcus pneumoniae TIGR4

76.549

80.427

0.616

Multiple sequence alignment