Detailed information NTG1119861

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EL076_RS00535
• Genome accession: NZ_LR134275
• Coordinates: 88068..90518 (+)
• Length: 816 a.a.
• NCBI ID: WP_048788058.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 83068..95518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS00510	ahpF	83295..84439 (-)	1145	Protein_63	alkyl hydroperoxide reductase subunit F	-
EL076_RS00515 (NCTC12167_00104)	rpsB	84801..85568 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
EL076_RS00520 (NCTC12167_00105)	tsf	85679..86719 (+)	1041	WP_126428896.1	translation elongation factor Ts	-
EL076_RS00525 (NCTC12167_00106)	-	86825..87295 (-)	471	WP_126428897.1	small multi-drug export protein	-
EL076_RS00530 (NCTC12167_00107)	-	87612..88067 (+)	456	WP_003092291.1	CtsR family transcriptional regulator	-
EL076_RS00535 (NCTC12167_00108)	clpC	88068..90518 (+)	2451	WP_048788058.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
EL076_RS00540 (NCTC12167_00109)	pbp3	90647..91903 (-)	1257	WP_126428898.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
EL076_RS00545 (NCTC12167_00110)	pbp3	92048..93295 (-)	1248	WP_197716140.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90245.47 Da
• Isoelectric Point: 5.8173

>NTDB_id=1119861 EL076_RS00535 WP_048788058.1 88068..90518(+) (clpC) [Streptococcus vestibularis strain NCTC12167]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEAMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGSIRKEAKREITSLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQEISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGNQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=1119861 EL076_RS00535 WP_048788058.1 88068..90518(+) (clpC) [Streptococcus vestibularis strain NCTC12167]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACTTAACCTTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCGAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGCTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGCATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTACACCAAAGACTTAACGGCAGTAGCTGAGTCAGGTGCCCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACAAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTGGCACAACGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAAATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCGAATATTTTGAAACCTGCTCTAGCACGTGGGACCCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCAGTTGAGACAGCGGTCAAGGCGGCCCACCGTTATTTGACGAGTAAAAACTTACCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTAGTATCAGAAAAGAAGCCAAACGTGAGATAACATCTTTGGATGAAG
CACTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGACGAAGCAGTTTCGGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGTTTTGATATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTCCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGACGGTGTTTTGACAGATAGCCGTGGTCGTAAGGTTGACTTTTCAAACACTATCATCATTATGAC
CTCAAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACCGTTGGTTTTGGAGCCCAAGAAATTTCTCATAATCACCAAG
CTATGCAGTCACGTATTATGGAAGAACTTAAGAAAGCCTACCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTTGAGGAAGAGCAGCTTCGTGAGATTGTCAAGATTATGGTGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCCCTTAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGATAAATTATCTGAGCTCTTACTAGGTAACCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (377-460)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	94.975	100	0.95
clpC	Streptococcus thermophilus LMD-9	94.853	100	0.949
clpC	Streptococcus mutans UA159	72.794	100	0.728
clpC	Streptococcus pneumoniae TIGR4	67.034	100	0.67
clpC	Streptococcus pneumoniae Rx1	67.034	100	0.67
clpC	Streptococcus pneumoniae D39	67.034	100	0.67
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	47.023	100	0.474
clpE	Streptococcus mutans UA159	48.243	76.716	0.37