Detailed information NTG1119748

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: EL077_RS03000
• Genome accession: NZ_LR134273
• Coordinates: 616242..618497 (-)
• Length: 751 a.a.
• NCBI ID: WP_126436461.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. equi strain NCTC12091
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 611242..623497

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL077_RS02985 (NCTC12091_00605)	ileS	612017..614815 (+)	2799	WP_126436459.1	isoleucine--tRNA ligase	-
EL077_RS02990 (NCTC12091_00606)	-	615284..615586 (-)	303	WP_012515246.1	DUF1827 family protein	-
EL077_RS02995 (NCTC12091_00607)	-	615648..616094 (-)	447	WP_014622508.1	NUDIX hydrolase	-
EL077_RS03000 (NCTC12091_00608)	clpE	616242..618497 (-)	2256	WP_126436461.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
EL077_RS03005 (NCTC12091_00609)	-	618779..619009 (+)	231	WP_012515249.1	DUF1797 family protein	-
EL077_RS03010 (NCTC12091_00610)	-	619454..620716 (-)	1263	WP_126436463.1	LPXTG cell wall anchor domain-containing protein	-
EL077_RS03015 (NCTC12091_00611)	-	621063..621746 (+)	684	WP_126436465.1	amino acid ABC transporter permease	-
EL077_RS03020 (NCTC12091_00612)	-	621748..622485 (+)	738	WP_126436467.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83854.24 Da
• Isoelectric Point: 5.6727

>NTDB_id=1119748 EL077_RS03000 WP_126436461.1 616242..618497(-) (clpE) [Streptococcus equi subsp. equi strain NCTC12091]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYTGNQKAQQQSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNHTQPAQETNKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRTPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLRIVHLMLDDVNQRLAHNSIHLDVTEKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPTEKNLRAVLTSNGHITIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=1119748 EL077_RS03000 WP_126436461.1 616242..618497(-) (clpE) [Streptococcus equi subsp. equi strain NCTC12091]
ATGCTTTGTCAAAACTGTAATTTAAACGAATCAACTATTCATCTTTATACAAGTATTAACGGAAAGCAAAGACAGATTGA
TCTGTGCCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCCTGGGAGGCTATACTGGCAATCAAAAGG
CCCAGCAGCAGTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTACCGTCCCAATCACACACAGCCAGC
ACAAGAGACTAACAAAGGTTTGCTTGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGATCCTG
TCATCGGACGTGACGATGAGATTATCCGCGTGATCGAGATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGA
GAACCAGGTGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGCGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAAGAAATCCGCAAGCGCCATGACGTGATTCTATTTATTGATGAAATCCATGAAATTGTGGGAGCTGGT
GCAGTTGGTGACGGCAGCATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
GACCACTCTCAATGAATACCGCATCATCGAAAAGGACGCAGCCCTTGAGCGACGCATGCAGCCGGTTAAGGTGGATGAGC
CTTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCCGCCAACCTATCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACT
AGATGAGGCTGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATCGACAAGCGTTTGATTGAGGCAG
AAAACCTTAAGGCACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATCACTGACAAGACCATCGAAGCAATCGTTGAGCAAAA
AACTAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGATGCTGTTGATAAAATTGCAAAAGCTATCCGTCGTAATCGTGTTGGACTGGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGGCCAACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCTATTGAGCTTTT
TGGCTCTGCTGATAATATGATTCGCTTTGACATGTCTGAATATATGGAAAAGCATGCTGTGGCTAAGCTTGTAGGTGCCC
CTCCAGGCTACGTTGGCTATGAGGAGGCAGGGCAGTTAACAGAGCAGGTACGCCGCACCCCTTACTCGCTCATTTTGTTA
GATGAGATTGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGTCGATTAACCGACGGACA
GGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAAGCCTCAGTCG
GCTTTGGTGCTGCTAGAGAAGGACGGACAAACTCTGTCCTAGGTGAGCTTAGTCATTTCTTTAGTCCCGAATTTATGAAC
CGCTTTGACGGGATTATTGAGTTTCAGCCGCTAAGCAAGGACAATCTGCTACGTATCGTTCACTTAATGCTTGATGACGT
TAATCAGCGCCTTGCTCACAATAGCATTCACCTTGATGTGACCGAAAAGGTCAAGGAAAAGCTCGTCGAGCTAGGCTATG
ATCCCAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGATTACATTGAGGATGCCATTACAGACTTTTACCTTGAG
CACCCAACTGAAAAGAACCTGCGAGCTGTTTTGACCTCTAATGGACACATTACAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (295-392)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.677	99.068	0.839
clpE	Streptococcus pneumoniae Rx1	82.072	100	0.823
clpE	Streptococcus pneumoniae D39	82.072	100	0.823
clpE	Streptococcus pneumoniae R6	82.072	100	0.823
clpE	Streptococcus pneumoniae TIGR4	81.939	100	0.822
clpC	Lactococcus lactis subsp. cremoris KW2	76.776	97.47	0.748
clpC	Bacillus subtilis subsp. subtilis str. 168	49.926	90.146	0.45
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.027	88.815	0.409
clpC	Streptococcus pneumoniae Rx1	48.065	82.557	0.397
clpC	Streptococcus pneumoniae D39	48.065	82.557	0.397
clpC	Streptococcus pneumoniae TIGR4	47.903	82.557	0.395
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus mutans UA159	47.182	82.69	0.39
clpC	Streptococcus thermophilus LMG 18311	46.19	83.888	0.387