Detailed information NTG1119747

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL077_RS02885
• Genome accession: NZ_LR134273
• Coordinates: 592193..593230 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. equi strain NCTC12091
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 587193..598230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL077_RS02860 (NCTC12091_00580)	-	587506..588837 (+)	1332	WP_126436449.1	dipeptidase	-
EL077_RS02865 (NCTC12091_00581)	arcC	588855..589805 (+)	951	WP_111689942.1	carbamate kinase	-
EL077_RS02870 (NCTC12091_00582)	asnA	590025..591017 (+)	993	WP_126436451.1	aspartate--ammonia ligase	-
EL077_RS02875 (NCTC12091_00583)	rsmD	591186..591725 (+)	540	WP_111692279.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL077_RS02880 (NCTC12091_00584)	coaD	591715..592215 (+)	501	WP_111692280.1	pantetheine-phosphate adenylyltransferase	-
EL077_RS02885 (NCTC12091_00585)	sepM	592193..593230 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
EL077_RS02890 (NCTC12091_00586)	-	593850..594464 (+)	615	WP_111692281.1	YutD family protein	-
EL077_RS02895 (NCTC12091_00587)	rlmN	594468..595550 (+)	1083	WP_126436453.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL077_RS02900 (NCTC12091_00588)	-	595973..596422 (-)	450	WP_228269161.1	peptidase	-
EL077_RS02905 (NCTC12091_00589)	-	596822..597352 (+)	531	WP_012515230.1	Dps family protein	-
EL077_RS02910 (NCTC12091_00590)	-	597725..597958 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=1119747 EL077_RS02885 WP_014622492.1 592193..593230(+) (sepM) [Streptococcus equi subsp. equi strain NCTC12091]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=1119747 EL077_RS02885 WP_014622492.1 592193..593230(+) (sepM) [Streptococcus equi subsp. equi strain NCTC12091]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTAGTGAGCCTCAGTCGGGCCACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGACTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTATCAGGCCCTTACTCTAGCAGGCAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701