Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   EL077_RS00805 Genome accession   NZ_LR134273
Coordinates   139413..141854 (+) Length   813 a.a.
NCBI ID   WP_126436219.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain NCTC12091     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 134413..146854
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL077_RS00775 (NCTC12091_00156) rpsB 134604..135374 (-) 771 WP_012677249.1 30S ribosomal protein S2 -
  EL077_RS00780 (NCTC12091_00157) ahpF 135835..137367 (-) 1533 WP_111689774.1 alkyl hydroperoxide reductase subunit F -
  EL077_RS00785 (NCTC12091_00158) ahpC 137388..137948 (-) 561 WP_126436215.1 alkyl hydroperoxide reductase subunit C -
  EL077_RS00795 - 138579..138782 (+) 204 WP_012514799.1 cold-shock protein -
  EL077_RS00800 (NCTC12091_00161) - 138952..139413 (+) 462 WP_126436217.1 CtsR family transcriptional regulator -
  EL077_RS00805 (NCTC12091_00162) clpC 139413..141854 (+) 2442 WP_126436219.1 AAA family ATPase Regulator
  EL077_RS00810 - 142204..142350 (-) 147 WP_080312399.1 putative holin-like toxin -
  EL077_RS00815 (NCTC12091_00165) - 142630..143061 (+) 432 WP_111692107.1 hypothetical protein -
  EL077_RS00820 (NCTC12091_00167) - 143196..143618 (+) 423 WP_126436221.1 hypothetical protein -
  EL077_RS00825 (NCTC12091_00169) - 143847..144278 (+) 432 WP_012677255.1 hypothetical protein -
  EL077_RS00830 (NCTC12091_00170) - 144280..145569 (+) 1290 WP_126436223.1 lipase family protein -
  EL077_RS00835 (NCTC12091_00171) - 145551..145943 (+) 393 WP_126436225.1 hypothetical protein -
  EL077_RS00840 (NCTC12091_00172) - 145924..146214 (+) 291 WP_021320276.1 hypothetical protein -
  EL077_RS00845 (NCTC12091_00173) groES 146514..146801 (+) 288 WP_012514806.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90400.22 Da        Isoelectric Point: 6.4367

>NTDB_id=1119740 EL077_RS00805 WP_126436219.1 139413..141854(+) (clpC) [Streptococcus equi subsp. equi strain NCTC12091]
MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKSTAVTE
DDMLHTLSKLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDHQTMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLK
IGVSRGKLAFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1119740 EL077_RS00805 WP_126436219.1 139413..141854(+) (clpC) [Streptococcus equi subsp. equi strain NCTC12091]
GTGATGATTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAAGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCATATTTTATTAGCTATGGTAGCTGTTGACCATTCCTTAGCGGCCATGGTGTTAAGCGAATTTGAACGAA
AGATTAGGGCTGAAGAGTATGAGGCTGCTGCTATTTTAGCCATGGGAAAAAGTCCCAAAGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTACTCTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTCTGTTAGAGTTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGCAAAATCATCTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACTCTTGATGCAGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGTGCTACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAGGACGCAGCCCTTTCTCGTCGCTTTGCCAAAATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTGTCCATACTGCTGTGAAGCTGGCTCGGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACACCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAATCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAAGCTATCAGGTATTCCCCTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
GAATCTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ACCAGTCAGGCATTCGCACAGGCAGGCGTCCGATTGGCTCCTTTATGTTTCTTGGTCCAACTGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGATATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCCCGTCTTAATGGGGCTCCTCCTGGCTATGTTGGCTATGATGAGGGAGGAGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCGGTCATGACCATCAAACAATGGAAA
AGCGTATTTTGGAGGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAGAAGGTGGTCTTCCATAGC
CTAACACAGGAAAACATGCGTGATGTGGTGAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTGTCTGAAGCTGGTTACGATGTTGAAATGGGCGCTCGCCCACTTCGTC
GCACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGAGTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGCTAGCTTTTGATATCGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA lid domain (AAA_lid_9)

(374-461)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(95-131)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-51)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

74.785

100

0.748
  clpC Streptococcus thermophilus LMD-9

72.059

100

0.723
  clpC Streptococcus thermophilus LMG 18311

71.814

100

0.721
  clpC Streptococcus pneumoniae Rx1

65.848

100

0.659
  clpC Streptococcus pneumoniae D39

65.848

100

0.659
  clpC Streptococcus pneumoniae TIGR4

65.725

100

0.658
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.623

100

0.499
  clpC Bacillus subtilis subsp. subtilis str. 168

43.832

100

0.45

Multiple sequence alignment