Detailed information NTG1119527

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EL071_RS10125
• Genome accession: NZ_LR134265
• Coordinates: 1962033..1963106 (-)
• Length: 357 a.a.
• NCBI ID: WP_000790649.1
• Uniprot ID: A0AB38VS22
• Organism: Streptococcus agalactiae strain NCTC8184
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1957033..1968106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL071_RS10105 (NCTC8184_02010)	-	1958305..1958820 (-)	516	WP_000919737.1	VanZ family protein	-
EL071_RS10110 (NCTC8184_02011)	rlmN	1958820..1959926 (-)	1107	WP_001124996.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL071_RS10115 (NCTC8184_02012)	-	1959977..1960555 (-)	579	WP_001224500.1	YutD-like domain-containing protein	-
EL071_RS10120 (NCTC8184_02013)	-	1960624..1961958 (-)	1335	WP_000137519.1	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
EL071_RS10125 (NCTC8184_02014)	sepM	1962033..1963106 (-)	1074	WP_000790649.1	SepM family pheromone-processing serine protease	Regulator
EL071_RS10130 (NCTC8184_02015)	coaD	1963096..1963581 (-)	486	WP_000161889.1	pantetheine-phosphate adenylyltransferase	-
EL071_RS10135 (NCTC8184_02016)	-	1963578..1963868 (-)	291	WP_115356926.1	hypothetical protein	-
EL071_RS10140 (NCTC8184_02017)	rsmD	1963880..1964419 (-)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EL071_RS10150 (NCTC8184_02018)	-	1964550..1964999 (+)	450	WP_000592264.1	bacteriocin transport accessory protein	-
EL071_RS10155 (NCTC8184_02019)	asnA	1965044..1966036 (-)	993	WP_000748010.1	aspartate--ammonia ligase	-
EL071_RS10160 (NCTC8184_02020)	-	1966151..1967215 (-)	1065	WP_115356927.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39145.34 Da
• Isoelectric Point: 10.4286

>NTDB_id=1119527 EL071_RS10125 WP_000790649.1 1962033..1963106(-) (sepM) [Streptococcus agalactiae strain NCTC8184]
MKNKDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVSSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1119527 EL071_RS10125 WP_000790649.1 1962033..1963106(-) (sepM) [Streptococcus agalactiae strain NCTC8184]
GTGAAGAATAAAGATCCAAAAAGAAAACATAAAAGTTTGCTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTGGTGAGGCTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATCATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTAGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGCACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (241-307)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658