Detailed information NTG1119463

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL095_RS04830
• Genome accession: NZ_LR134264
• Coordinates: 1073857..1074900 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain NCTC7944
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1068857..1079900

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL095_RS04805 (SAMEA3500277_00985)	-	1069860..1070579 (+)	720	WP_023015863.1	glutamine amidotransferase	-
EL095_RS04810 (SAMEA3500277_00986)	-	1070662..1071648 (-)	987	WP_002481667.1	aromatic acid exporter family protein	-
EL095_RS04815 (SAMEA3500277_00987)	map	1071868..1072632 (+)	765	WP_060803962.1	type I methionyl aminopeptidase	-
EL095_RS04820 (SAMEA3500277_00988)	-	1072748..1073143 (+)	396	WP_002481665.1	hypothetical protein	-
EL095_RS04825 (SAMEA3500277_00989)	liaF	1073159..1073860 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
EL095_RS04830 (SAMEA3500277_00990)	vraS	1073857..1074900 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
EL095_RS04835 (SAMEA3500277_00991)	vraR	1074890..1075519 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
EL095_RS04840 (SAMEA3500277_00992)	-	1075590..1076168 (-)	579	WP_002481661.1	carbonic anhydrase	-
EL095_RS04845 (SAMEA3500277_00993)	-	1076376..1077452 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
EL095_RS04850 (SAMEA3500277_00994)	-	1077583..1077873 (-)	291	WP_002481659.1	hypothetical protein	-
EL095_RS04855 (SAMEA3500277_00995)	-	1077881..1078345 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
EL095_RS04860 (SAMEA3500277_00996)	-	1078569..1078775 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=1119463 EL095_RS04830 WP_002481663.1 1073857..1074900(+) (vraS) [Staphylococcus simulans strain NCTC7944]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=1119463 EL095_RS04830 WP_002481663.1 1073857..1074900(+) (vraS) [Staphylococcus simulans strain NCTC7944]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATTTTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCACTTGATCAGCAAATTCC
AACACTAGAAAAGATGGTCCAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862