Detailed information NTG1119360

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL075_RS04435
• Genome accession: NZ_LR134244
• Coordinates: 922019..923062 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain NCTC7291
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 917019..928062

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL075_RS04410 (NCTC7291_00910)	-	918075..918800 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
EL075_RS04415 (NCTC7291_00911)	-	918868..919854 (-)	987	WP_015364857.1	FUSC family protein	-
EL075_RS04420 (NCTC7291_00912)	map	920021..920776 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
EL075_RS04425 (NCTC7291_00913)	-	920920..921306 (+)	387	WP_002466133.1	DUF2543 family protein	-
EL075_RS04430 (NCTC7291_00914)	liaF	921321..922022 (+)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
EL075_RS04435 (NCTC7291_00915)	vraS	922019..923062 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
EL075_RS04440 (NCTC7291_00916)	vraR	923052..923681 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
EL075_RS04445 (NCTC7291_00917)	-	923740..924975 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
EL075_RS04450 (NCTC7291_00918)	-	925205..925489 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
EL075_RS04455 (NCTC7291_00919)	-	925496..925960 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
EL075_RS04460 (NCTC7291_00920)	-	926107..926310 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
EL075_RS04465 (NCTC7291_00921)	-	926323..927564 (+)	1242	WP_015364860.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=1119360 EL075_RS04435 WP_002466111.1 922019..923062(+) (vraS) [Staphylococcus warneri strain NCTC7291]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=1119360 EL075_RS04435 WP_002466111.1 922019..923062(+) (vraS) [Staphylococcus warneri strain NCTC7291]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948