Detailed information NTG1119325

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EL068_RS04650
• Genome accession: NZ_LR134242
• Coordinates: 962843..963886 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain NCTC4133
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 957843..968886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL068_RS04625 (NCTC4133_00942)	-	958899..959624 (+)	726	WP_023373124.1	type 1 glutamine amidotransferase	-
EL068_RS04630 (NCTC4133_00943)	-	959692..960678 (-)	987	WP_015364857.1	FUSC family protein	-
EL068_RS04635 (NCTC4133_00944)	map	960845..961600 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
EL068_RS04640 (NCTC4133_00945)	-	961744..962130 (+)	387	WP_002466133.1	DUF2543 family protein	-
EL068_RS04645 (NCTC4133_00946)	liaF	962145..962846 (+)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
EL068_RS04650 (NCTC4133_00947)	vraS	962843..963886 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
EL068_RS04655 (NCTC4133_00948)	vraR	963876..964505 (+)	630	WP_058710065.1	response regulator transcription factor	Regulator
EL068_RS04660 (NCTC4133_00949)	-	964564..965799 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
EL068_RS04665 (NCTC4133_00950)	-	966029..966313 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
EL068_RS04670 (NCTC4133_00951)	-	966320..966784 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
EL068_RS04675 (NCTC4133_00952)	-	966931..967134 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
EL068_RS04680 (NCTC4133_00953)	-	967147..968388 (+)	1242	WP_058710066.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=1119325 EL068_RS04650 WP_002466111.1 962843..963886(+) (vraS) [Staphylococcus warneri strain NCTC4133]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=1119325 EL068_RS04650 WP_002466111.1 962843..963886(+) (vraS) [Staphylococcus warneri strain NCTC4133]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTTCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGCAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948