Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EL068_RS04250 Genome accession   NZ_LR134242
Coordinates   884856..885572 (-) Length   238 a.a.
NCBI ID   WP_002466277.1    Uniprot ID   -
Organism   Staphylococcus warneri strain NCTC4133     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 879856..890572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL068_RS04230 (NCTC4133_00863) - 880744..880968 (+) 225 WP_002466256.1 sulfurtransferase TusA family protein -
  EL068_RS04235 (NCTC4133_00864) - 881109..882059 (+) 951 WP_002466257.1 LacI family DNA-binding transcriptional regulator -
  EL068_RS04240 (NCTC4133_00866) - 882360..883844 (+) 1485 WP_126510267.1 sucrose-6-phosphate hydrolase -
  EL068_RS04245 (NCTC4133_00867) - 883841..884797 (+) 957 WP_058709853.1 carbohydrate kinase family protein -
  EL068_RS04250 (NCTC4133_00868) agrA 884856..885572 (-) 717 WP_002466277.1 quorum-sensing response regulator AgrA Regulator
  EL068_RS04255 (NCTC4133_00869) agrC 885585..886874 (-) 1290 WP_058709854.1 quorum-sensing sensor histidine kinase AgrC -
  EL068_RS04260 (NCTC4133_00870) agrD 886900..887040 (-) 141 WP_058709855.1 cyclic lactone autoinducer peptide AgrD -
  EL068_RS04265 (NCTC4133_00871) - 887045..887608 (-) 564 WP_058709856.1 accessory gene regulator AgrB -
  EL068_RS04270 - 887925..888002 (+) 78 WP_015364840.1 delta-lysin family phenol-soluble modulin -
  EL068_RS04275 - 888069..888146 (+) 78 WP_015364841.1 delta-lysin family phenol-soluble modulin -
  EL068_RS04280 (NCTC4133_00874) - 888560..889345 (-) 786 WP_058709857.1 carbon-nitrogen family hydrolase -
  EL068_RS04285 (NCTC4133_00875) - 889462..890088 (-) 627 WP_002451574.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27897.92 Da        Isoelectric Point: 5.9175

>NTDB_id=1119324 EL068_RS04250 WP_002466277.1 884856..885572(-) (agrA) [Staphylococcus warneri strain NCTC4133]
MKIFICEDDPKQRENMASIIKNYIMIEEKPMELALATDDPYEVLEQSKNMNDIGCYFLDIQLEADINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKESNVETIELKRGSNSVYVQYDDIM
FFESSSKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVINRRNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1119324 EL068_RS04250 WP_002466277.1 884856..885572(-) (agrA) [Staphylococcus warneri strain NCTC4133]
ATGAAAATATTCATTTGCGAAGATGATCCAAAACAACGAGAAAATATGGCTTCAATTATTAAAAATTATATTATGATTGA
GGAAAAGCCTATGGAGCTTGCTCTCGCAACTGATGATCCTTATGAAGTGCTTGAGCAATCCAAAAATATGAATGACATCG
GTTGTTATTTCTTAGATATTCAACTTGAAGCTGATATAAATGGTATTAAATTAGGTAGTGAAATTCGAAAACATGATCCT
GTAGGTAATATCATTTTTGTAACAAGTCATAGTGAATTAACGTATCTCACTTTTGTTTATAAAGTGGCTGCAATGGATTT
TATATTCAAAGATGATCCTGCAGAACTGAAAACACGTATTATCGATTGTTTAGAAACAGCTCACACAAGACTTAAATTAT
TATCTAAAGAAAGTAATGTAGAAACAATAGAGTTAAAGCGTGGTAGTAATTCAGTTTATGTACAATATGACGATATTATG
TTTTTCGAATCATCTAGTAAATCACATCGATTAATTGCACATTTAGATAATAGACAAATCGAATTTTATGGTAACCTTAA
AGAATTAAGTCAATTAGATGACCGCTTCTTTAGATGTCATAATAGCTTTGTGATTAACCGAAGAAATATTGAGTCAATCG
ATTCTAAAGAACGCATTGTCTATTTTAAAAATAAAGAGCATTGTTATGCATCAGTTCGTAATGTCAAAAAGATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

93.697

100

0.937

Multiple sequence alignment