Detailed information    

insolico Bioinformatically predicted

Overview

Name   rcrP   Type   Regulator
Locus tag   EL020_RS06710 Genome accession   NZ_LR134203
Coordinates   1304992..1306806 (-) Length   604 a.a.
NCBI ID   WP_020916924.1    Uniprot ID   A0AB33AM14
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   regulate competence (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1282578..1323414 1304992..1306806 within 0


Gene organization within MGE regions


Location: 1282578..1323414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS06585 (NCTC11436_01387) yihA 1282578..1283171 (-) 594 WP_043895055.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL020_RS06590 (NCTC11436_01388) clpX 1283182..1284411 (-) 1230 WP_020916897.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL020_RS06600 (NCTC11436_01390) - 1284638..1285132 (-) 495 WP_020916898.1 dihydrofolate reductase -
  EL020_RS06605 (NCTC11436_01391) - 1285215..1286054 (-) 840 WP_126402585.1 thymidylate synthase -
  EL020_RS06610 (NCTC11436_01392) - 1286382..1287557 (+) 1176 WP_020916900.1 hydroxymethylglutaryl-CoA synthase -
  EL020_RS06615 (NCTC11436_01393) - 1287547..1288818 (+) 1272 WP_058813992.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EL020_RS06620 (NCTC11436_01394) - 1288981..1289424 (+) 444 WP_020916902.1 DUF1836 domain-containing protein -
  EL020_RS06625 (NCTC11436_01395) trhA 1289414..1290070 (+) 657 WP_020916903.1 PAQR family membrane homeostasis protein TrhA -
  EL020_RS06630 (NCTC11436_01396) fni 1290093..1291091 (-) 999 WP_111698839.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  EL020_RS06635 (NCTC11436_01397) - 1291088..1292086 (-) 999 WP_043895056.1 phosphomevalonate kinase -
  EL020_RS06640 (NCTC11436_01398) mvaD 1292088..1293023 (-) 936 WP_058832946.1 diphosphomevalonate decarboxylase -
  EL020_RS06645 (NCTC11436_01399) mvk 1293005..1293883 (-) 879 WP_111698845.1 mevalonate kinase -
  EL020_RS06650 (NCTC11436_01400) - 1293996..1294754 (-) 759 WP_126402586.1 amino acid ABC transporter ATP-binding protein -
  EL020_RS06655 (NCTC11436_01401) - 1294773..1295453 (-) 681 WP_058813998.1 amino acid ABC transporter permease -
  EL020_RS06660 (NCTC11436_01402) - 1295464..1296156 (-) 693 WP_058813999.1 amino acid ABC transporter permease -
  EL020_RS06665 (NCTC11436_01403) - 1296166..1297044 (-) 879 WP_111712854.1 transporter substrate-binding domain-containing protein -
  EL020_RS06670 (NCTC11436_01404) - 1297096..1298127 (-) 1032 WP_058814001.1 uroporphyrinogen decarboxylase family protein -
  EL020_RS06680 (NCTC11436_01406) - 1298714..1299628 (+) 915 WP_020916918.1 LysR family transcriptional regulator -
  EL020_RS06685 (NCTC11436_01407) - 1299690..1300535 (+) 846 WP_020916919.1 aldo/keto reductase -
  EL020_RS06690 (NCTC11436_01408) - 1300577..1301803 (-) 1227 WP_020916920.1 sensor histidine kinase -
  EL020_RS06695 (NCTC11436_01409) - 1301812..1302492 (-) 681 WP_126402587.1 response regulator transcription factor -
  EL020_RS06700 (NCTC11436_01410) - 1302495..1303130 (-) 636 WP_020916922.1 GTP pyrophosphokinase family protein -
  EL020_RS06705 (NCTC11436_01411) rcrQ 1303230..1305002 (-) 1773 WP_020916923.1 ABC transporter ATP-binding protein Regulator
  EL020_RS06710 (NCTC11436_01412) rcrP 1304992..1306806 (-) 1815 WP_020916924.1 ABC transporter ATP-binding protein Regulator
  EL020_RS06715 (NCTC11436_01413) rcrR 1306810..1307250 (-) 441 WP_043895256.1 MarR family winged helix-turn-helix transcriptional regulator Regulator
  EL020_RS06720 (NCTC11436_01414) - 1307395..1307805 (-) 411 WP_020916926.1 peptide deformylase -
  EL020_RS09910 - 1307802..1308014 (-) 213 WP_228380533.1 GNAT family N-acetyltransferase -
  EL020_RS09915 (NCTC11436_01415) - 1307996..1308310 (-) 315 WP_228380475.1 hypothetical protein -
  EL020_RS06730 (NCTC11436_01416) gdhA 1308468..1309817 (-) 1350 WP_043895060.1 NADP-specific glutamate dehydrogenase -
  EL020_RS06735 (NCTC11436_01417) - 1310054..1310551 (+) 498 WP_043895061.1 HdeD family acid-resistance protein -
  EL020_RS06740 (NCTC11436_01418) queF 1310588..1311079 (-) 492 WP_058814005.1 preQ(1) synthase -
  EL020_RS06745 queE 1311229..1311948 (-) 720 Protein_1319 7-carboxy-7-deazaguanine synthase QueE -
  EL020_RS06750 (NCTC11436_01421) queD 1311941..1312387 (-) 447 WP_061407985.1 6-carboxytetrahydropterin synthase QueD -
  EL020_RS06755 (NCTC11436_01422) queC 1312387..1313040 (-) 654 Protein_1321 7-cyano-7-deazaguanine synthase QueC -
  EL020_RS06760 (NCTC11436_01423) - 1313205..1314974 (-) 1770 WP_020916931.1 ABC transporter ATP-binding protein -
  EL020_RS06765 (NCTC11436_01424) - 1314977..1316716 (-) 1740 WP_020916932.1 ABC transporter ATP-binding protein -
  EL020_RS06770 (NCTC11436_01425) - 1316979..1317506 (-) 528 WP_126402588.1 hypothetical protein -
  EL020_RS06775 (NCTC11436_01426) - 1317546..1319414 (-) 1869 WP_126402589.1 ABC-F family ATP-binding cassette domain-containing protein -
  EL020_RS06780 (NCTC11436_01427) - 1319411..1320616 (-) 1206 WP_020916935.1 CCA tRNA nucleotidyltransferase -
  EL020_RS06785 (NCTC11436_01428) dapB 1320613..1321380 (-) 768 WP_020916936.1 4-hydroxy-tetrahydrodipicolinate reductase -
  EL020_RS06790 (NCTC11436_01429) - 1321405..1322253 (-) 849 WP_020916937.1 DegV family protein -
  EL020_RS06795 (NCTC11436_01430) - 1322253..1322633 (-) 381 WP_020916938.1 DUF1149 family protein -
  EL020_RS06800 (NCTC11436_01431) - 1322755..1323414 (-) 660 WP_020916939.1 glucosaminidase domain-containing protein -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 67041.98 Da        Isoelectric Point: 5.7821

>NTDB_id=1118972 EL020_RS06710 WP_020916924.1 1304992..1306806(-) (rcrP) [Streptococcus lutetiensis strain NCTC11436]
MLKIFKRLTAKEIIMMIIAVLFVCLNVFLDLKIPDYMSDITSLLSTQGTKAKDIFAWNLDAPGMRMVLLSLGSFAASVVV
GFLAARIAASFSTRLRDDIFHSVLDFSDAEIKKFSIPSLLTRTTNDITQIQLVFTMGLQVITKGPIMAIWAITKIADKNH
EWLMVLVVAVAVMILMLIFLLMMVMPKQRMIQKLTDKLNSITRESLTGIRVVRAYNAESYQDGKFAKANDNVTNFNLFIN
RSMALMSPVMTSISSGMTLAIYWIGAFLIEDIAIPKDPTKIAGAMQDKVNIFSDMVVYSSYAMQVVIGFMMMIIVFFILP
RAVVAAGRINEVLDTKPSVTYPEESKAQPAEKGSVEFDDVSFRYSEHSEAVLEHVSFKAKAGDTVAFIGSTGSGKSTLVN
LIPRFYDASEGTIKVDGVDVRDYDHDTLHKIVGYIPQKAVLFSGDIASNMDMGDSNSSPLDDDKMWEALDLAQGKDFVES
KEGQLKAKVSQGGQNFSGGQKQRLAIARALARKPEIIIFDDSFSALDYKTDRILRSQLKERTADMTKLIVAQRISTIMDA
DQILVLDEGKVVGQGTHEELLANNEVYREIAYSQLSKEELENGK

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=1118972 EL020_RS06710 WP_020916924.1 1304992..1306806(-) (rcrP) [Streptococcus lutetiensis strain NCTC11436]
ATGTTAAAAATTTTTAAACGTTTAACGGCAAAAGAAATCATCATGATGATTATTGCCGTCTTATTTGTGTGTTTGAATGT
TTTCTTGGATTTAAAAATTCCAGATTACATGTCTGATATCACATCTTTACTCTCAACTCAAGGAACAAAAGCAAAAGATA
TTTTTGCTTGGAATCTAGATGCCCCAGGTATGCGTATGGTCTTGCTTTCTTTAGGAAGTTTTGCAGCCTCTGTGGTTGTC
GGATTCTTAGCCGCACGCATCGCAGCAAGTTTCAGTACGCGTTTGCGTGATGATATTTTCCATAGTGTTTTGGACTTTTC
AGATGCGGAAATTAAGAAATTTTCAATTCCAAGTCTTTTAACACGTACAACAAATGACATTACTCAAATTCAGTTGGTCT
TTACCATGGGACTTCAAGTTATTACCAAAGGACCAATTATGGCAATCTGGGCTATTACGAAGATTGCTGATAAAAACCAT
GAGTGGTTGATGGTGCTGGTTGTAGCAGTGGCTGTCATGATTTTAATGTTGATTTTCTTGCTCATGATGGTAATGCCAAA
ACAACGCATGATTCAAAAATTAACGGATAAATTGAACAGTATTACACGTGAATCTTTGACTGGTATTCGTGTTGTTCGTG
CTTACAATGCCGAAAGTTATCAAGATGGTAAATTTGCTAAAGCCAATGATAACGTGACAAACTTTAACCTCTTTATCAAC
CGTTCAATGGCTTTGATGTCACCAGTTATGACAAGTATTTCAAGCGGGATGACTTTGGCAATTTATTGGATTGGTGCTTT
CCTGATTGAAGATATTGCTATTCCAAAAGACCCAACTAAGATTGCAGGTGCCATGCAAGATAAGGTAAATATCTTCTCAG
ATATGGTGGTTTATTCCTCATATGCCATGCAAGTTGTTATTGGTTTTATGATGATGATTATCGTTTTCTTCATTCTTCCC
CGTGCGGTTGTCGCTGCAGGTCGTATTAATGAAGTCTTGGATACGAAGCCATCTGTTACTTATCCTGAAGAAAGTAAAGC
TCAGCCGGCCGAAAAAGGTTCTGTTGAATTTGATGACGTGTCTTTCCGCTACAGCGAGCATTCGGAAGCTGTTTTGGAAC
ATGTTTCCTTTAAGGCTAAAGCAGGTGATACGGTTGCCTTTATCGGATCAACAGGTTCTGGTAAATCTACTCTAGTTAAT
TTGATTCCTCGTTTCTATGATGCAAGTGAAGGAACAATCAAAGTTGACGGTGTTGACGTTCGTGATTACGATCATGACAC
CCTTCACAAGATTGTTGGTTACATTCCGCAAAAAGCTGTGCTCTTTAGTGGAGACATTGCTTCAAATATGGACATGGGTG
ACAGCAATAGTTCACCGCTTGATGATGATAAGATGTGGGAAGCACTTGATTTGGCACAAGGTAAAGATTTCGTTGAAAGT
AAAGAGGGTCAACTAAAAGCTAAAGTCTCCCAAGGTGGTCAAAACTTCTCAGGTGGTCAAAAACAACGCTTGGCGATTGC
GCGTGCCCTTGCTCGTAAACCTGAAATTATCATCTTTGATGATTCATTCTCAGCGCTTGATTATAAGACTGACCGAATCC
TTCGTTCTCAATTGAAAGAACGTACAGCTGACATGACTAAGTTGATTGTTGCCCAACGTATTTCAACAATCATGGATGCT
GATCAGATCTTAGTCTTGGATGAAGGTAAAGTAGTTGGTCAAGGTACTCACGAAGAATTGCTTGCAAATAATGAAGTTTA
TCGTGAAATTGCCTATTCACAATTATCTAAGGAGGAATTAGAAAATGGAAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(16-270)

ABC transporter (ABC_tran)

(372-522)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rcrP Streptococcus mutans UA159

67.273

100

0.674

Multiple sequence alignment