Detailed information NTG1118864

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EL036_RS14145
• Genome accession: NZ_LR134193
• Coordinates: 2731408..2732295 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NCTC13616
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2726408..2737295

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL036_RS14110	-	2726426..2726514 (+)	89	Protein_2650	hypothetical protein	-
EL036_RS14115 (NCTC13616_02683)	-	2726622..2727119 (-)	498	WP_001065267.1	glutathione peroxidase	-
EL036_RS14120 (NCTC13616_02684)	-	2727129..2727389 (-)	261	WP_072434822.1	hypothetical protein	-
EL036_RS14130	-	2727771..2727884 (-)	114	WP_072384844.1	hypothetical protein	-
EL036_RS14135 (NCTC13616_02685)	-	2728548..2730548 (-)	2001	WP_000776746.1	ABC transporter permease	-
EL036_RS14140 (NCTC13616_02686)	-	2730545..2731300 (-)	756	WP_000923771.1	ABC transporter ATP-binding protein	-
EL036_RS14145 (NCTC13616_02687)	braS	2731408..2732295 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EL036_RS14150 (NCTC13616_02688)	braR	2732306..2732971 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EL036_RS14155 (NCTC13616_02689)	-	2732997..2733197 (-)	201	WP_000604723.1	hypothetical protein	-
EL036_RS14160 (NCTC13616_02690)	-	2733395..2734819 (+)	1425	WP_000953731.1	alkaline phosphatase	-
EL036_RS14880 (NCTC13616_02691)	-	2734879..2734980 (-)	102	WP_000731972.1	SE2200 family small protein	-
EL036_RS14170 (NCTC13616_02692)	-	2735102..2735557 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
EL036_RS14175 (NCTC13616_02693)	-	2735803..2736564 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1118864 EL036_RS14145 WP_000143420.1 2731408..2732295(-) (braS) [Staphylococcus aureus strain NCTC13616]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1118864 EL036_RS14145 WP_000143420.1 2731408..2732295(-) (braS) [Staphylococcus aureus strain NCTC13616]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993