Detailed information    

insolico Bioinformatically predicted

Overview

Name   rec2   Type   Machinery gene
Locus tag   ELZ63_RS03770 Genome accession   NZ_LR134171
Coordinates   745478..747844 (+) Length   788 a.a.
NCBI ID   WP_061724336.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12699     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 740478..752844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ63_RS03745 (NCTC12699_00746) - 740827..742125 (-) 1299 WP_005657733.1 N-acetylmuramoyl-L-alanine amidase -
  ELZ63_RS03750 (NCTC12699_00747) tsaE 742133..742609 (-) 477 WP_061724334.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ELZ63_RS03755 (NCTC12699_00748) folK 742685..743167 (-) 483 WP_061724335.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  ELZ63_RS03760 (NCTC12699_00749) pcnB 743176..744534 (-) 1359 WP_014550610.1 polynucleotide adenylyltransferase PcnB -
  ELZ63_RS09325 - 744560..744718 (-) 159 WP_154231907.1 hypothetical protein -
  ELZ63_RS03765 (NCTC12699_00750) dksA 744781..745218 (-) 438 WP_005657744.1 RNA polymerase-binding protein DksA -
  ELZ63_RS03770 (NCTC12699_00751) rec2 745478..747844 (+) 2367 WP_061724336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ELZ63_RS03775 (NCTC12699_00752) msbA 747885..749648 (+) 1764 WP_065245426.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  ELZ63_RS03780 (NCTC12699_00753) lpxK 749721..750719 (+) 999 WP_005657751.1 tetraacyldisaccharide 4'-kinase -
  ELZ63_RS03785 (NCTC12699_00754) kdsB 750790..751554 (+) 765 WP_048951387.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 788 a.a.        Molecular weight: 89187.75 Da        Isoelectric Point: 9.9451

>NTDB_id=1118742 ELZ63_RS03770 WP_061724336.1 745478..747844(+) (rec2) [Haemophilus influenzae strain NCTC12699]
MKLNLITLAVLLIVSDLTLLFLPQPLLLPWQVALVIALVLIFLFIFLRRNFLVSLAFFVASLGYFHYSALSLLQQAQNIT
AQKQVVTFKIQEILHQQDYQTLIATATLANNLQEQRIFLNWKAKEVPQLSEIWQAEISLRPLSARLNFGGFDRQQWYFSK
GITAVGTVKSAVKIADVSSLRAEKLQQVKKQTEGLSLQGLLIALAFGERAWLDKTTWSIYQQTNTAHLIAISGLHIGLAM
GIGFCLARVVQVFFPTRFIHPYFPLVFGVLFALIYAYLAGFSVPTFRAISALVFVLFIQIMRRHYSPIQLFTVVVGFLLF
CDPLMPLSVSFWLSCGAVGCLILWYRYVPFSLFQWKNRPFSPKVRWILSLFHLQFGLLLFFTPLQLFLFNGLSLSGFLAN
LMAVPIYSFLLVPLILFAVFTNGTMFSWQLANKLAEGITGLISVFQGNWLTVSFNLALGLTSLCAGIFMLIIWSIYREPE
VLSLSWQIKRAKFFTLNLSKPLLKNEQINVLRCSFGIILLCFTILLFKQLSKPTWQVDTLDVGQGLATLIVKNGKGILYD
TGSSWRGGSMAELEILPYLQREGIVLEKLILSHDDNDHAGGASTILKAYPNVELITPSRKNYGENYRTFCTAGRDWHWQG
LHFQILSPHNVVTRADNPHSCVILVDDGKNSVLLTGDAEAKNEQIFARTLGKIDVLQVGHHGSKTSTSEYLLSQVRPDVA
IISSGRWNPWKFPHYSVMERLHRYKSAVENTAVSGQVRVNFFQDRLEIQQARTKFSPWYARVIGLSKE

Nucleotide


Download         Length: 2367 bp        

>NTDB_id=1118742 ELZ63_RS03770 WP_061724336.1 745478..747844(+) (rec2) [Haemophilus influenzae strain NCTC12699]
ATGAAATTAAACTTAATAACTTTAGCTGTCTTGTTAATTGTCTCGGATTTAACGTTGTTATTTCTACCGCAACCGTTGCT
ATTGCCTTGGCAAGTTGCTCTCGTTATTGCGCTTGTTTTGATTTTTCTTTTTATTTTCTTGCGTAGAAATTTCTTAGTTA
GCCTTGCTTTTTTTGTTGCCTCTCTTGGCTATTTTCATTATTCGGCTTTGAGTTTATTACAACAAGCTCAAAATATTACC
GCTCAAAAGCAAGTGGTAACTTTTAAGATTCAAGAAATTTTGCACCAACAGGATTATCAAACGCTTATCGCCACAGCAAC
ATTGGCGAATAATTTGCAAGAACAACGAATTTTCTTAAATTGGAAAGCGAAAGAGGTGCCTCAATTATCGGAAATTTGGC
AAGCTGAAATTTCTTTACGTCCCCTTTCTGCACGATTAAATTTTGGTGGGTTTGATCGGCAACAATGGTATTTTTCAAAA
GGAATTACGGCTGTTGGAACGGTAAAAAGTGCGGTGAAAATTGCGGATGTTTCATCATTGCGAGCAGAAAAATTGCAACA
AGTGAAAAAACAAACAGAAGGGTTGTCCTTACAAGGTTTATTGATTGCCTTAGCTTTTGGCGAACGGGCTTGGTTAGATA
AAACCACTTGGTCAATTTACCAACAAACCAATACCGCACATCTTATTGCTATTTCTGGCTTACATATTGGGTTGGCTATG
GGAATTGGATTTTGCTTGGCGCGTGTTGTGCAAGTATTTTTCCCCACCCGTTTTATTCATCCTTATTTTCCTTTAGTTTT
TGGTGTTTTATTTGCTTTAATTTATGCGTATTTGGCTGGTTTTAGCGTGCCAACTTTTCGTGCCATTTCAGCACTTGTTT
TCGTTTTATTTATTCAAATAATGAGGCGACATTATTCGCCCATTCAGCTTTTTACGGTGGTTGTCGGATTCTTGCTTTTC
TGCGATCCATTAATGCCGCTTTCGGTCAGTTTTTGGCTTTCTTGTGGGGCAGTTGGGTGTTTGATCCTCTGGTATCGTTA
TGTGCCTTTTTCACTTTTTCAATGGAAAAATCGCCCTTTTTCTCCAAAAGTGCGGTGGATTTTGAGTTTATTTCATTTGC
AATTTGGGTTATTGCTCTTTTTTACGCCTTTGCAACTTTTTCTATTTAATGGCTTATCGTTGAGTGGATTTTTAGCCAAT
CTTATGGCGGTTCCAATTTATAGTTTTTTGCTTGTGCCATTAATTTTATTTGCCGTTTTTACTAACGGCACAATGTTTTC
TTGGCAACTAGCAAACAAGTTAGCCGAAGGAATTACTGGGTTAATTTCTGTTTTTCAAGGGAATTGGCTCACGGTTTCAT
TTAATTTAGCATTGGGTTTAACCTCACTTTGTGCAGGAATTTTTATGTTAATTATTTGGAGCATTTACCGAGAACCTGAG
GTTTTATCATTGAGCTGGCAAATAAAACGAGCAAAATTTTTTACATTAAATCTCAGTAAGCCTTTGCTAAAAAATGAACA
AATCAACGTTTTGCGATGTTCTTTCGGCATTATCTTACTGTGTTTTACGATTTTGTTGTTTAAACAATTGAGCAAACCAA
CTTGGCAGGTAGATACTTTAGATGTGGGGCAGGGGTTGGCAACGCTGATTGTGAAAAATGGCAAAGGGATTCTTTATGAT
ACGGGTTCTTCTTGGCGAGGTGGAAGTATGGCTGAGTTGGAAATTTTGCCTTATTTACAAAGAGAAGGGATTGTTTTGGA
AAAATTGATTTTAAGCCACGACGATAACGATCACGCAGGTGGTGCTTCGACAATTTTAAAGGCGTATCCCAATGTGGAAT
TGATTACCCCTTCACGGAAAAACTATGGGGAAAATTACCGCACTTTTTGTACTGCTGGGCGTGATTGGCATTGGCAAGGG
TTGCATTTTCAAATACTTTCTCCTCACAACGTTGTGACACGAGCTGATAATCCCCATTCTTGTGTGATTTTAGTCGATGA
TGGAAAGAATAGCGTTTTGCTAACTGGCGATGCTGAAGCAAAAAATGAGCAAATTTTTGCCCGCACTTTAGGCAAAATCG
ATGTGTTGCAAGTGGGGCATCATGGGAGTAAAACATCAACAAGTGAATACTTGCTTTCTCAGGTTAGACCAGATGTAGCG
ATTATTTCTAGTGGGCGTTGGAATCCGTGGAAATTCCCTCATTATTCGGTTATGGAAAGGCTTCATCGCTATAAAAGTGC
GGTAGAAAATACCGCTGTTTCGGGGCAAGTGCGGGTAAATTTTTTTCAAGACCGATTAGAAATCCAGCAAGCTCGCACAA
AATTTTCCCCTTGGTATGCACGTGTAATTGGATTATCAAAGGAATAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(204-473)

Domain of unknown function (DUF4131) (DUF4131)

(28-171)

Metallo-beta-lactamase superfamily (Lactamase_B)

(541-725)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rec2 Haemophilus influenzae Rd KW20

97.716

100

0.977

Multiple sequence alignment