Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EL050_RS06855 Genome accession   NZ_LR134165
Coordinates   1358482..1359120 (+) Length   212 a.a.
NCBI ID   WP_003180627.1    Uniprot ID   A0A6I7TLB4
Organism   Bacillus paralicheniformis strain NCTC8721     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1353482..1364120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL050_RS06825 (NCTC8721_01394) - 1354121..1355197 (+) 1077 WP_152342713.1 ABC transporter ATP-binding protein -
  EL050_RS06830 (NCTC8721_01395) - 1355199..1356122 (+) 924 WP_025808307.1 ATP-binding cassette domain-containing protein -
  EL050_RS06835 (NCTC8721_01396) - 1356352..1356930 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  EL050_RS06840 (NCTC8721_01397) spxA 1357108..1357503 (+) 396 WP_003180621.1 transcriptional regulator SpxA -
  EL050_RS06845 (NCTC8721_01398) - 1357534..1358196 (-) 663 WP_020450936.1 TerC family protein -
  EL050_RS06850 - 1358375..1358500 (+) 126 Protein_1294 hypothetical protein -
  EL050_RS06855 (NCTC8721_01399) mecA 1358482..1359120 (+) 639 WP_003180627.1 adaptor protein MecA Regulator
  EL050_RS06860 (NCTC8721_01400) - 1359357..1360661 (+) 1305 WP_025811640.1 glycosyl hydrolase family 8 -
  EL050_RS06865 (NCTC8721_01402) - 1360784..1361900 (+) 1117 Protein_1297 tripartite tricarboxylate transporter substrate binding protein -
  EL050_RS06870 (NCTC8721_01403) - 1362003..1362458 (+) 456 WP_025811638.1 tripartite tricarboxylate transporter TctB family protein -
  EL050_RS06875 (NCTC8721_01404) - 1362481..1363986 (+) 1506 WP_003180636.1 tripartite tricarboxylate transporter permease -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25044.99 Da        Isoelectric Point: 4.1840

>NTDB_id=1118584 EL050_RS06855 WP_003180627.1 1358482..1359120(+) (mecA) [Bacillus paralicheniformis strain NCTC8721]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSISGCQTTLYSHENRYYLFV
DFSELPDEEVENQLSILLEYASESKTTIHMLKEYGTLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=1118584 EL050_RS06855 WP_003180627.1 1358482..1359120(+) (mecA) [Bacillus paralicheniformis strain NCTC8721]
ATGGAAATCGAAAGAATAAACGAACATACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGATAAGGGATTGGAAATCATTGTGACAAGAGCTCAGCTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAGTTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTATCAGCGGCTGCCAAACGACATTGTACTCTCACGAGAACCGCTATTATTTATTCGTG
GATTTCAGTGAACTGCCTGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAGTATGCCTCAGAATCAAAGACGAC
GATTCATATGCTGAAAGAGTATGGAACACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTCGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7TLB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.028

100

0.84

Multiple sequence alignment