Detailed information NTG1118454

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ELZ55_RS09870
• Genome accession: NZ_LR134139
• Coordinates: 1925330..1926373 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCTC4163
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1920330..1931373

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ55_RS09840 (NCTC4163_01853)	-	1920752..1922008 (-)	1257	WP_001793428.1	aminopeptidase	-
ELZ55_RS09845 (NCTC4163_01854)	-	1922011..1922211 (-)	201	WP_000180463.1	DUF1128 family protein	-
ELZ55_RS09850 (NCTC4163_01855)	-	1922358..1922822 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ELZ55_RS09855 (NCTC4163_01856)	-	1922829..1923104 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ELZ55_RS09860 (NCTC4163_01857)	-	1923382..1924599 (+)	1218	WP_042727579.1	YihY/virulence factor BrkB family protein	-
ELZ55_RS09865 (NCTC4163_01858)	vraR	1924711..1925340 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ELZ55_RS09870 (NCTC4163_01859)	vraS	1925330..1926373 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ELZ55_RS09875 (NCTC4163_01860)	liaF	1926370..1927071 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ELZ55_RS09880 (NCTC4163_01861)	-	1927086..1927472 (-)	387	WP_001110179.1	hypothetical protein	-
ELZ55_RS09885 (NCTC4163_01862)	map	1927689..1928447 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
ELZ55_RS09895 (NCTC4163_01863)	-	1928978..1929964 (+)	987	WP_042727578.1	FUSC family protein	-
ELZ55_RS09905 (NCTC4163_01864)	-	1930395..1930808 (-)	414	WP_001549145.1	hypothetical protein	-
ELZ55_RS09910	-	1930837..1930947 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1118454 ELZ55_RS09870 WP_001017131.1 1925330..1926373(-) (vraS) [Staphylococcus aureus strain NCTC4163]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1118454 ELZ55_RS09870 WP_001017131.1 1925330..1926373(-) (vraS) [Staphylococcus aureus strain NCTC4163]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1