Detailed information NTG1118302

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ELZ51_RS10380
• Genome accession: NZ_LR134094
• Coordinates: 2060071..2062515 (-)
• Length: 814 a.a.
• NCBI ID: WP_126427442.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2055071..2067515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ51_RS10360 (NCTC4669_02186)	-	2055428..2056924 (+)	1497	WP_126427438.1	C69 family dipeptidase	-
ELZ51_RS10365 (NCTC4669_02187)	-	2057258..2057725 (+)	468	WP_003053009.1	8-oxo-dGTP diphosphatase	-
ELZ51_RS10370 (NCTC4669_02188)	groL	2057942..2059567 (-)	1626	WP_126427440.1	chaperonin GroEL	-
ELZ51_RS10375 (NCTC4669_02189)	groES	2059603..2059893 (-)	291	WP_115245554.1	co-chaperone GroES	-
ELZ51_RS10380 (NCTC4669_02190)	clpC	2060071..2062515 (-)	2445	WP_126427442.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ELZ51_RS10385 (NCTC4669_02191)	-	2062515..2062976 (-)	462	WP_126427444.1	CtsR family transcriptional regulator	-
ELZ51_RS10390	-	2063173..2063376 (-)	204	WP_003053018.1	cold-shock protein	-
ELZ51_RS10395 (NCTC4669_02193)	-	2063786..2064760 (+)	975	WP_126427446.1	amidohydrolase family protein	-
ELZ51_RS10400 (NCTC4669_02194)	-	2064891..2065346 (+)	456	WP_003053027.1	MarR family winged helix-turn-helix transcriptional regulator	-
ELZ51_RS10405 (NCTC4669_02195)	-	2065333..2066724 (+)	1392	WP_126427448.1	GNAT family N-acetyltransferase	-
ELZ51_RS10410 (NCTC4669_02196)	-	2066840..2067118 (+)	279	WP_003053031.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90308.97 Da
• Isoelectric Point: 6.6848

>NTDB_id=1118302 ELZ51_RS10380 WP_126427442.1 2060071..2062515(-) (clpC) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKDQVSHID
FRPQSKTLTNLLQFAQAISHVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYAIKDKGNGEPRLADLRKAIEIHAGYSK
EMIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVVGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAD
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQKDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKTYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPMMATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=1118302 ELZ51_RS10380 WP_126427442.1 2060071..2062515(-) (clpC) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAATTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGATCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCTATGGGCAAAAGCCCTAAAGACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCATGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCTGGTTATG
CTATCAAGGATAAAGGAAACGGAGAACCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGTAAG
GAAATGATTAAGGCTATCCACGAGTTGCGTAAACCAAAGAAAACCAAGAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGATTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTTTTAGAGCCAGTTG
TTGGCCGTGATGCTGAAGTATCACGGATGATCCAAGTACTGAGTCGTAAAACCAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTATGGTCTTGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAACTGCAAGA
CATGCGTGTTCTAGAATTAGATATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAGATTATTCTCTTTGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACGCTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGTGGAACTCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGCCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTGAT
CAGGCTGTTAGAACTGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCTATTGATTTGTT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTAGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGATATCTTGACGACCTTGAGCAAGTTATCAGGTATCCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAAAAGATGCTGTCTCAGCTATTTCTCGAGCGATTCGTC
GTAATCAGTCAGGCATCCGTACAGGTAAACGTCCGATTGGTTCCTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACT
GAGTTGGCTAAAGCCTTGGCAGAAGTTCTCTTTGACGATGCGTCTGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
AAAATTTGCGGCTTCTCGTCTTAATGGCGCACCTCCAGGCTATGTCGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTACTCCGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACATACTCTTACAA
GTACTTGATGACGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAACACTATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAACTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGATAATATGAGAGAAGTGGTCAAGATTATGGTGCAGCCGATGATGGCTACTTTGGCAGAAAAAGGCAT
TACCCTTAAATTCCAGCCAATGGCCCTCAAATATTTATCAGAAGAAGGGTACGATGTAGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGTCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (376-462)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-133)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.507	99.877	0.764
clpC	Streptococcus thermophilus LMD-9	72.917	100	0.731
clpC	Streptococcus thermophilus LMG 18311	72.672	100	0.729
clpC	Streptococcus pneumoniae TIGR4	66.79	99.877	0.667
clpC	Streptococcus pneumoniae Rx1	66.79	99.877	0.667
clpC	Streptococcus pneumoniae D39	66.79	99.877	0.667
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.561	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	42.84	100	0.437