Detailed information NTG1118179

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ELZ58_RS09750
• Genome accession: NZ_LR134091
• Coordinates: 1916342..1917385 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCTC4137
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1911342..1922385

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ58_RS09720 (NCTC4137_01830)	-	1911764..1913020 (-)	1257	WP_001793428.1	aminopeptidase	-
ELZ58_RS09725 (NCTC4137_01831)	-	1913023..1913223 (-)	201	WP_000180463.1	DUF1128 family protein	-
ELZ58_RS09730 (NCTC4137_01832)	-	1913370..1913834 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ELZ58_RS09735 (NCTC4137_01833)	-	1913841..1914116 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ELZ58_RS09740 (NCTC4137_01834)	-	1914394..1915611 (+)	1218	WP_042727579.1	YihY/virulence factor BrkB family protein	-
ELZ58_RS09745 (NCTC4137_01835)	vraR	1915723..1916352 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ELZ58_RS09750 (NCTC4137_01836)	vraS	1916342..1917385 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ELZ58_RS09755 (NCTC4137_01837)	liaF	1917382..1918083 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ELZ58_RS09760 (NCTC4137_01838)	-	1918098..1918484 (-)	387	WP_001110179.1	hypothetical protein	-
ELZ58_RS09765 (NCTC4137_01839)	map	1918701..1919459 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
ELZ58_RS09775 (NCTC4137_01840)	-	1919990..1920976 (+)	987	WP_042727578.1	FUSC family protein	-
ELZ58_RS09785 (NCTC4137_01841)	-	1921407..1921820 (-)	414	WP_001549145.1	hypothetical protein	-
ELZ58_RS09790	-	1921849..1921959 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1118179 ELZ58_RS09750 WP_001017131.1 1916342..1917385(-) (vraS) [Staphylococcus aureus strain NCTC4137]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1118179 ELZ58_RS09750 WP_001017131.1 1916342..1917385(-) (vraS) [Staphylococcus aureus strain NCTC4137]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1