Detailed information NTG0111817

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NJ8700_RS08110
• Genome accession: NZ_CP009230
• Coordinates: 1747245..1749815 (+)
• Length: 856 a.a.
• NCBI ID: WP_005702108.1
• Uniprot ID: -
• Organism: Aggregatibacter aphrophilus NJ8700
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1742245..1754815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NJ8700_RS08080 (NJ8700_08260)	tusA	1742378..1742617 (+)	240	WP_005702115.1	sulfurtransferase TusA	-
NJ8700_RS08085 (NJ8700_08265)	-	1742646..1742894 (+)	249	WP_005702113.1	accessory factor UbiK family protein	-
NJ8700_RS08090 (NJ8700_08270)	nadR	1742979..1744250 (+)	1272	WP_005702112.1	multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR	-
NJ8700_RS08095 (NJ8700_08275)	-	1744267..1744950 (+)	684	WP_005702111.1	metallophosphoesterase	-
NJ8700_RS08100 (NJ8700_08280)	-	1745053..1746282 (+)	1230	WP_005702110.1	aromatic amino acid transporter	-
NJ8700_RS08105 (NJ8700_08285)	-	1746377..1747000 (-)	624	WP_005702109.1	helix-hairpin-helix domain-containing protein	-
NJ8700_RS08110 (NJ8700_08290)	clpC	1747245..1749815 (+)	2571	WP_005702108.1	ATP-dependent chaperone ClpB	Regulator
NJ8700_RS08115 (NJ8700_08295)	-	1749914..1750411 (-)	498	WP_005702107.1	surface-adhesin E family protein	-
NJ8700_RS08120 (NJ8700_08300)	purM	1750594..1751634 (+)	1041	WP_005702106.1	phosphoribosylformylglycinamidine cyclo-ligase	-
NJ8700_RS08125 (NJ8700_08305)	purN	1751634..1752272 (+)	639	WP_005702104.1	phosphoribosylglycinamide formyltransferase	-
NJ8700_RS08130 (NJ8700_08310)	-	1752314..1753129 (-)	816	WP_005702103.1	Cof-type HAD-IIB family hydrolase	-
NJ8700_RS08135 (NJ8700_08315)	-	1753289..1753975 (+)	687	WP_005702102.1	DNA utilization protein GntX	-
NJ8700_RS08140 (NJ8700_08320)	nfuA	1754087..1754671 (+)	585	WP_005702101.1	Fe-S biogenesis protein NfuA	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95759.27 Da
• Isoelectric Point: 5.2055

>NTDB_id=111817 NJ8700_RS08110 WP_005702108.1 1747245..1749815(+) (clpC) [Aggregatibacter aphrophilus NJ8700]
MNIEKFTTKFQQAIAEAQSLAIGKDNQFIEPVHLLSALLNQQDGSVAPILTASGVNVAILRNELNNELAKLPQVSGNGGD
VQLSRQLLNILNLCDKLAQQRQDKFISSELFLLAALEEKGAVSEILKKCGAKKEQILQAIDHIRGGQNVNDQNAEESRQA
LEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLKELAQEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVGEPSVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPQPLDRLDRRIIQLKLEQQALQKEDDDASRKRLEMLEKELAEKEREYAELEEVWKSEKAALSGTQHIKAELE
NARTQMEQARRAGDLSKMSELQYGKIPELEKQLAAAEGAEGKEMSLLRYRVTDEEIAEVLSRATGIPVSKMMEGEKEKLL
RMEEELHKRVIGQNEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLAKFLFDSEDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQGNQEESYDEMKALVMSVVSQHFRPEFINRIDETVVFHPLNKDNIRAIAEIQLKRLINRMESRGYVLHFTDDTLN
FISEIGYDPIYGARPLKRAIQQEIENPLAQQILSGSLLPEKPITVDYVDGKIVAKQ

Nucleotide

• Length: 2571 bp

>NTDB_id=111817 NJ8700_RS08110 WP_005702108.1 1747245..1749815(+) (clpC) [Aggregatibacter aphrophilus NJ8700]
ATGAATATTGAAAAATTTACGACCAAATTCCAACAAGCCATTGCTGAAGCGCAATCTTTGGCGATTGGCAAAGATAATCA
ATTTATTGAACCGGTGCATTTATTGAGCGCGTTGTTAAATCAACAAGATGGTTCTGTAGCGCCGATTTTAACCGCAAGTG
GCGTGAACGTTGCCATATTGCGCAACGAACTCAACAACGAACTTGCCAAACTTCCGCAAGTGTCCGGCAATGGCGGTGAT
GTACAACTTTCCCGTCAGTTGCTTAACATCTTGAATTTATGCGACAAATTGGCACAACAACGGCAGGATAAATTTATTTC
CTCCGAACTCTTTTTACTTGCCGCCTTAGAAGAAAAAGGCGCCGTCAGTGAGATACTGAAAAAGTGCGGTGCGAAAAAAG
AACAAATTTTACAAGCCATCGATCATATTCGTGGAGGACAAAACGTGAATGATCAAAACGCGGAAGAAAGCCGCCAAGCC
TTAGAAAAATATACTATCGACTTAACCGCCCGTGCGGAAAGTGGCAAATTGGATCCGGTGATTGGGCGTGATGAAGAAAT
CCGCCGCACCATTCAAGTGTTACAACGCCGCACCAAAAACAACCCGGTGCTTATCGGTGAACCGGGTGTGGGTAAAACCG
CCATTGTAGAAGGGTTGGCGCAACGTATTGTGAACGGCGAAGTACCGGAAGGCTTGAAAAATAAACGCGTGCTTTCACTT
GATATGGGGGCGTTAATCGCTGGGGCAAAGTATCGCGGTGAATTTGAAGAACGCCTGAAAGCCGTATTGAAAGAATTAGC
TCAAGAAGAAGGTCGTGTCATTTTATTTATTGATGAAATTCACACCATGGTCGGTGCGGGTAAAACCGACGGTGCTATGG
ATGCGGGTAACTTGTTAAAACCAAGTTTGGCGCGTGGTGAATTGCATTGTGTGGGCGCGACCACATTAGACGAATACCGC
CAATACATTGAGAAAGATGCGGCACTTGAACGTCGTTTCCAAAAAGTGTTTGTGGGTGAGCCGAGTGTGGAAGACACCAT
CGCCATTTTGCGCGGCTTAAAAGAACGTTATGAAATCCATCACCACGTGCAAATTACCGACCCGGCTATTGTGGCAGCGG
CAACATTGTCTCATCGTTACATTTCCGATCGCCAGTTACCGGATAAAGCCATCGACTTGATCGACGAAGCCGCATCCAGC
ATTCGGATGGAAATCGACTCCAAACCACAGCCGTTGGATCGCTTGGATCGCCGTATTATCCAACTCAAATTGGAACAACA
GGCGTTACAAAAAGAAGATGACGATGCCAGCCGTAAACGCTTGGAGATGTTAGAAAAAGAATTAGCGGAAAAAGAACGGG
AATACGCTGAATTAGAAGAAGTGTGGAAATCTGAAAAAGCCGCGCTTTCGGGTACCCAACACATTAAAGCTGAATTGGAA
AACGCCCGTACCCAAATGGAACAAGCCCGTCGTGCCGGTGATTTGAGCAAAATGTCCGAATTGCAATACGGTAAAATTCC
GGAATTGGAAAAACAATTAGCGGCAGCAGAAGGTGCGGAAGGCAAAGAAATGAGCCTATTACGCTATCGTGTTACCGACG
AGGAAATTGCTGAAGTGCTTTCCCGTGCTACCGGCATTCCGGTCTCCAAAATGATGGAAGGCGAAAAAGAAAAACTCTTG
CGCATGGAAGAAGAATTACACAAACGGGTTATCGGGCAAAACGAAGCCGTGGATGCTGTGGCGAATGCCATTCGTCGTAG
CCGTGCCGGTCTTTCTGATCCGAATCGCCCGATTGGTTCCTTCTTGTTCTTAGGACCAACCGGTGTGGGTAAAACCGAAT
TGTGCAAAACCTTGGCGAAATTCTTGTTTGATAGCGAAGATGCCATGGTGCGTATCGACATGTCCGAATTCATGGAAAAA
CACAGTGTATCCCGCTTGGTCGGTGCACCTCCGGGCTACGTGGGCTATGAAGAAGGCGGTTATTTAACCGAGGCTGTGCG
TCGTCGCCCGTATTCCGTGATTTTGCTCGACGAAGTGGAAAAAGCGCACCACGATGTATTCAACATCTTGTTGCAAGTGT
TGGATGACGGCCGCTTAACCGACGGACAAGGCAGAACTGTGGATTTCCGCAATACGGTGGTAATCATGACGTCTAACTTG
GGTTCCGATTTGATTCAAGGCAACCAAGAAGAAAGCTACGACGAAATGAAAGCGTTAGTGATGTCTGTGGTGAGCCAGCA
TTTCCGTCCGGAATTTATTAACCGAATTGACGAAACCGTGGTGTTCCATCCGTTGAATAAAGACAACATTCGTGCCATTG
CGGAAATTCAGTTAAAACGCTTAATCAACCGCATGGAAAGCCGTGGCTATGTGTTGCACTTTACTGACGACACCCTCAAT
TTCATCAGCGAAATCGGCTATGACCCGATTTACGGCGCACGTCCGTTAAAACGTGCCATTCAACAAGAAATTGAGAACCC
GTTAGCGCAACAAATCCTTTCCGGCAGTTTGTTACCGGAAAAACCGATTACCGTGGATTACGTTGACGGCAAGATTGTGG
CAAAACAATAA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (342-443)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (765-844)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.181	100	0.479
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.086	100	0.44
clpE	Streptococcus mutans UA159	49.267	79.673	0.393
clpE	Streptococcus pneumoniae TIGR4	49.118	79.439	0.39
clpE	Streptococcus pneumoniae D39	48.899	79.556	0.389
clpE	Streptococcus pneumoniae Rx1	48.899	79.556	0.389
clpE	Streptococcus pneumoniae R6	48.899	79.556	0.389
clpC	Lactococcus lactis subsp. cremoris KW2	46.089	83.645	0.386