Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ELZ50_RS11030 Genome accession   NZ_LR134087
Coordinates   2119971..2120687 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain NCTC7121     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2114971..2125687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ50_RS11000 (NCTC7121_02070) - 2115191..2115817 (+) 627 WP_000522384.1 nitroreductase family protein -
  ELZ50_RS11005 (NCTC7121_02071) - 2116178..2116963 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  ELZ50_RS15025 hld 2117559..2117639 (-) 81 WP_000046022.1 delta-hemolysin -
  ELZ50_RS11015 (NCTC7121_02073) agrB 2117929..2118498 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  ELZ50_RS11020 (NCTC7121_02074) agrD 2118495..2118635 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ELZ50_RS11025 (NCTC7121_02075) agrC 2118660..2119952 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  ELZ50_RS11030 (NCTC7121_02076) agrA 2119971..2120687 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  ELZ50_RS11035 - 2120759..2120868 (+) 110 Protein_2064 hypothetical protein -
  ELZ50_RS11040 (NCTC7121_02077) - 2121056..2122015 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  ELZ50_RS11045 (NCTC7121_02078) - 2122012..2123496 (-) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  ELZ50_RS11050 (NCTC7121_02079) - 2123645..2124595 (-) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=1118062 ELZ50_RS11030 WP_000688498.1 2119971..2120687(+) (agrA) [Staphylococcus aureus strain NCTC7121]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1118062 ELZ50_RS11030 WP_000688498.1 2119971..2120687(+) (agrA) [Staphylococcus aureus strain NCTC7121]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment