Detailed information NTG1118060

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ELZ50_RS10145
• Genome accession: NZ_LR134087
• Coordinates: 1984517..1985560 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCTC7121
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1979517..1990560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ50_RS10115 (NCTC7121_01910)	-	1979939..1981195 (-)	1257	WP_001793428.1	aminopeptidase	-
ELZ50_RS10120 (NCTC7121_01911)	-	1981198..1981398 (-)	201	WP_000180463.1	DUF1128 family protein	-
ELZ50_RS10125 (NCTC7121_01912)	-	1981545..1982009 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ELZ50_RS10130 (NCTC7121_01913)	-	1982016..1982291 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ELZ50_RS10135 (NCTC7121_01914)	-	1982569..1983786 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
ELZ50_RS10140 (NCTC7121_01915)	vraR	1983898..1984527 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ELZ50_RS10145 (NCTC7121_01916)	vraS	1984517..1985560 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ELZ50_RS10150 (NCTC7121_01917)	liaF	1985557..1986258 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ELZ50_RS10155 (NCTC7121_01918)	-	1986273..1986659 (-)	387	WP_001110179.1	hypothetical protein	-
ELZ50_RS10160 (NCTC7121_01919)	map	1986876..1987634 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
ELZ50_RS10170 (NCTC7121_01920)	-	1988165..1989151 (+)	987	WP_000999713.1	FUSC family protein	-
ELZ50_RS10180 (NCTC7121_01921)	-	1989582..1989995 (-)	414	WP_001549145.1	hypothetical protein	-
ELZ50_RS10185	-	1990024..1990134 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1118060 ELZ50_RS10145 WP_001017131.1 1984517..1985560(-) (vraS) [Staphylococcus aureus strain NCTC7121]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1118060 ELZ50_RS10145 WP_001017131.1 1984517..1985560(-) (vraS) [Staphylococcus aureus strain NCTC7121]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1