Detailed information NTG1118022

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ELZ49_RS14230
• Genome accession: NZ_LR134086
• Coordinates: 2742907..2743794 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NCTC13142
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2737907..2748794

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ49_RS14195	-	2737925..2738013 (+)	89	Protein_2662	hypothetical protein	-
ELZ49_RS14200 (NCTC13142_02716)	-	2738121..2738618 (-)	498	WP_001065267.1	glutathione peroxidase	-
ELZ49_RS14205 (NCTC13142_02717)	-	2738628..2738888 (-)	261	WP_072434822.1	hypothetical protein	-
ELZ49_RS14215	-	2739270..2739383 (-)	114	WP_072384844.1	hypothetical protein	-
ELZ49_RS14220 (NCTC13142_02718)	-	2740047..2742047 (-)	2001	WP_000776746.1	ABC transporter permease	-
ELZ49_RS14225 (NCTC13142_02719)	-	2742044..2742799 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ELZ49_RS14230 (NCTC13142_02720)	braS	2742907..2743794 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ELZ49_RS14235 (NCTC13142_02721)	braR	2743805..2744470 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ELZ49_RS14240 (NCTC13142_02722)	-	2744496..2744696 (-)	201	WP_000604723.1	hypothetical protein	-
ELZ49_RS14245 (NCTC13142_02723)	-	2744894..2746318 (+)	1425	WP_000953731.1	alkaline phosphatase	-
ELZ49_RS14980 (NCTC13142_02724)	-	2746378..2746479 (-)	102	WP_000731972.1	SE2200 family small protein	-
ELZ49_RS14255 (NCTC13142_02725)	-	2746601..2747056 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
ELZ49_RS14260 (NCTC13142_02726)	-	2747302..2748063 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1118022 ELZ49_RS14230 WP_000143420.1 2742907..2743794(-) (braS) [Staphylococcus aureus strain NCTC13142]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1118022 ELZ49_RS14230 WP_000143420.1 2742907..2743794(-) (braS) [Staphylococcus aureus strain NCTC13142]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993