Detailed information NTG1117981

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ELZ52_RS14445
• Genome accession: NZ_LR134085
• Coordinates: 2742538..2743425 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NCTC12233
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2737538..2748425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ52_RS14410	-	2737557..2737649 (+)	93	WP_010956583.1	hypothetical protein	-
ELZ52_RS14415 (NCTC12233_02655)	-	2737757..2738254 (-)	498	WP_001065268.1	glutathione peroxidase	-
ELZ52_RS14420	-	2738264..2738524 (-)	261	WP_001789910.1	hypothetical protein	-
ELZ52_RS14430	-	2738906..2739019 (-)	114	WP_011447078.1	hypothetical protein	-
ELZ52_RS14435 (NCTC12233_02656)	-	2739678..2741678 (-)	2001	WP_000776751.1	ABC transporter permease	-
ELZ52_RS14440 (NCTC12233_02657)	-	2741675..2742430 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ELZ52_RS14445 (NCTC12233_02658)	braS	2742538..2743425 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ELZ52_RS14450 (NCTC12233_02659)	braR	2743436..2744101 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ELZ52_RS14455 (NCTC12233_02660)	-	2744127..2744327 (-)	201	WP_000604728.1	hypothetical protein	-
ELZ52_RS14460 (NCTC12233_02661)	-	2744525..2745949 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ELZ52_RS15190 (NCTC12233_02662)	-	2746009..2746110 (-)	102	WP_000731972.1	SE2200 family small protein	-
ELZ52_RS14470 (NCTC12233_02663)	-	2746232..2746687 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ELZ52_RS14475 (NCTC12233_02664)	-	2746932..2747693 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1117981 ELZ52_RS14445 WP_000143419.1 2742538..2743425(-) (braS) [Staphylococcus aureus strain NCTC12233]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1117981 ELZ52_RS14445 WP_000143419.1 2742538..2743425(-) (braS) [Staphylococcus aureus strain NCTC12233]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997