Detailed information NTG1117822

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ELZ47_RS07825
• Genome accession: NZ_LR134002
• Coordinates: 1579516..1580376 (-)
• Length: 286 a.a.
• NCBI ID: WP_126435724.1
• Uniprot ID: A0AAJ5NMR0
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1574516..1585376

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS07795 (NCTC10904_01533)	-	1574579..1575340 (-)	762	WP_126435720.1	hypothetical protein	-
ELZ47_RS07800 (NCTC10904_01534)	-	1575408..1575965 (-)	558	WP_126435721.1	hypothetical protein	-
ELZ47_RS07805 (NCTC10904_01535)	-	1576101..1577996 (-)	1896	WP_126435722.1	ABC-F family ATP-binding cassette domain-containing protein	-
ELZ47_RS07815 (NCTC10904_01536)	-	1578249..1578614 (-)	366	WP_126435723.1	hypothetical protein	-
ELZ47_RS07820 (NCTC10904_01537)	-	1578619..1579338 (-)	720	WP_002904157.1	matrixin family metalloprotease	-
ELZ47_RS07825 (NCTC10904_01538)	endA	1579516..1580376 (-)	861	WP_126435724.1	DNA/RNA non-specific endonuclease	Machinery gene
ELZ47_RS07830 (NCTC10904_01539)	-	1580435..1580617 (-)	183	WP_002917490.1	DNA-directed RNA polymerase subunit beta	-
ELZ47_RS07835 (NCTC10904_01540)	murA	1580610..1581890 (-)	1281	WP_002917491.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ELZ47_RS07840 (NCTC10904_01541)	-	1581958..1582188 (-)	231	WP_002897901.1	DUF1146 family protein	-
ELZ47_RS07845 (NCTC10904_01542)	-	1582363..1582785 (-)	423	WP_126435725.1	F0F1 ATP synthase subunit epsilon	-
ELZ47_RS07850 (NCTC10904_01543)	atpD	1582793..1584199 (-)	1407	WP_126435726.1	F0F1 ATP synthase subunit beta	-
ELZ47_RS07855 (NCTC10904_01544)	-	1584238..1585119 (-)	882	WP_002895995.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31326.09 Da
• Isoelectric Point: 10.1352

>NTDB_id=1117822 ELZ47_RS07825 WP_126435724.1 1579516..1580376(-) (endA) [Streptococcus sanguinis strain NCTC 10904]
MKRKTSQKRNSKSLQGWAGLTLALILALAGYFWGQEGQQPLQSPNSEIRVGQVQDQGTPSRELAESVLTDAVRAQLKGSI
EWNGAGAFIVNGNKTDLDAGISSKPYADNKTKLVQGKTLPTVANAFLSKSTRQYKKREETGNANTSWVPAGWHQLKNLPG
EYNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWSNQANETDSTGQNYYETKIRKALDKNKRVRYRVTLIYATEI
DLVPVGSHLEAKSSDGSLEFNVFIPNVQKGIRLDYNSGRVSLDRGS

Nucleotide

• Length: 861 bp

>NTDB_id=1117822 ELZ47_RS07825 WP_126435724.1 1579516..1580376(-) (endA) [Streptococcus sanguinis strain NCTC 10904]
ATGAAAAGAAAGACTAGTCAGAAAAGGAATTCTAAGAGCCTGCAAGGCTGGGCTGGGCTGACTTTAGCCTTGATTTTAGC
TCTGGCTGGCTATTTCTGGGGACAGGAAGGTCAGCAGCCACTTCAGAGCCCAAATTCAGAAATCAGAGTTGGGCAAGTCC
AAGATCAGGGCACCCCTAGTCGGGAACTGGCTGAGAGCGTTCTGACGGATGCTGTCCGAGCTCAACTCAAAGGCAGCATT
GAATGGAACGGAGCTGGCGCCTTTATCGTGAATGGAAATAAGACAGACTTGGATGCGGGGATTTCTAGTAAGCCCTACGC
TGACAATAAGACCAAGCTTGTTCAAGGGAAAACCCTTCCGACGGTGGCGAATGCCTTTTTATCGAAGTCTACCCGCCAGT
ACAAAAAACGGGAAGAAACTGGAAATGCCAACACTTCATGGGTACCGGCAGGTTGGCATCAACTCAAGAACCTCCCTGGT
GAGTACAATCATGCTGTGGACCGCGGACATCTCTTGGCCTATTCGCTGATCGGTGGTTTGAAGGGCTTTGATGCCTCTAC
CAGCAATCCTGCCAATATTGCTGTGCAGACGGCTTGGTCCAACCAAGCCAATGAAACTGATTCGACAGGGCAGAATTACT
ACGAGACAAAGATCCGGAAGGCTCTTGATAAGAACAAGCGGGTGCGCTACCGGGTAACCTTGATTTATGCTACGGAGATT
GATTTAGTGCCGGTTGGCTCACATTTAGAGGCCAAGTCCAGCGATGGCAGTCTGGAATTCAATGTCTTTATCCCGAATGT
GCAAAAAGGGATTCGCCTGGACTATAATAGTGGCAGGGTCAGTCTGGATAGAGGTTCTTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (88-249)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	74.554	78.322	0.584
endA	Streptococcus pneumoniae D39	74.554	78.322	0.584
endA	Streptococcus pneumoniae R6	74.554	78.322	0.584
endA	Streptococcus pneumoniae TIGR4	74.554	78.322	0.584