Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ELZ47_RS00905 Genome accession   NZ_LR134002
Coordinates   164654..167083 (+) Length   809 a.a.
NCBI ID   WP_126434991.1    Uniprot ID   A0AAJ5NFX1
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 159654..172083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS00870 (NCTC10904_00170) nusG 159659..160195 (+) 537 WP_002894018.1 transcription termination/antitermination protein NusG -
  ELZ47_RS00875 (NCTC10904_00171) - 160281..161045 (-) 765 WP_125330752.1 hypothetical protein -
  ELZ47_RS00885 (NCTC10904_00173) rpsB 161552..162334 (+) 783 WP_126434988.1 30S ribosomal protein S2 -
  ELZ47_RS00890 (NCTC10904_00174) tsf 162406..163449 (+) 1044 WP_002928238.1 translation elongation factor Ts -
  ELZ47_RS00895 (NCTC10904_00175) - 163554..163982 (-) 429 WP_164549625.1 hypothetical protein -
  ELZ47_RS00900 (NCTC10904_00176) - 164189..164653 (+) 465 WP_126434990.1 CtsR family transcriptional regulator -
  ELZ47_RS00905 (NCTC10904_00177) clpC 164654..167083 (+) 2430 WP_126434991.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ELZ47_RS00910 (NCTC10904_00178) - 167211..167921 (+) 711 WP_072074720.1 DUF4272 domain-containing protein -
  ELZ47_RS00915 (NCTC10904_00179) - 167963..168448 (+) 486 WP_164549532.1 ECF transporter S component -
  ELZ47_RS00920 (NCTC10904_00180) - 168432..168833 (+) 402 WP_126434992.1 DUF4430 domain-containing protein -
  ELZ47_RS00925 (NCTC10904_00181) - 169018..170076 (+) 1059 WP_125330753.1 AAA family ATPase -
  ELZ47_RS00930 (NCTC10904_00182) pnuC 170098..170913 (+) 816 WP_126434993.1 nicotinamide riboside transporter PnuC -
  ELZ47_RS00935 (NCTC10904_00183) - 170970..171752 (+) 783 WP_125330755.1 NUDIX domain-containing protein -

Sequence

Protein


Download         Length: 809 a.a.        Molecular weight: 89580.25 Da        Isoelectric Point: 5.4547

>NTDB_id=1117793 ELZ47_RS00905 WP_126434991.1 164654..167083(+) (clpC) [Streptococcus sanguinis strain NCTC 10904]
MKYSKALIESLEAAQLLAGHFTTDYLESWHLLIALANNPYSVAGSVLNEFPVEVDGFEEAAFQITGQAYQKDGHFELLPF
SYRLEELFEEAGQIAEAVRAKHVGTEHVLLAMLFDRGTLASRILEFTGFNYEDKEQGPKISDLRKVLEQRAGWGKEDIKA
IRSLNKGVMAAKQTMANMMGMPASTSGGLEDYTRDLTELARDGRLEPVIGRDQEISRIVQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPAELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVSIEEPNVADSIAILQGLRKSYEDHHKVQISDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVQNRGPQNYEQSDLTPVDQALMVADFKKVSKLLKQEQQPKLYKLKVEEGDVL
ATLSALSGIPVQKLTQTDAKKYLNLETELHKRVIGQDEAISAISRAIRRNQSGIRSSKRPIGSFMFLGPTGVGKTELAKA
LAESLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
QLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDIRLDHANMEKRMLEELKKAYRPEFINRIDEKVVFHSLSAE
DMQEVVKVMVKPLIASLAEKGIELKFQSSALKLLAQEGYDVEMGARPLRRTLQTQVEDKLSELLLTGDLAAGQTLKVGVK
AGQLKFEVA

Nucleotide


Download         Length: 2430 bp        

>NTDB_id=1117793 ELZ47_RS00905 WP_126434991.1 164654..167083(+) (clpC) [Streptococcus sanguinis strain NCTC 10904]
ATGAAATACTCAAAAGCCTTAATAGAAAGCTTGGAAGCAGCCCAGCTCTTGGCCGGCCATTTTACGACAGATTATCTGGA
ATCATGGCATCTGTTGATTGCTCTGGCTAATAATCCCTACAGCGTTGCTGGCTCAGTCCTCAATGAGTTTCCTGTGGAAG
TTGATGGATTTGAAGAAGCAGCTTTTCAGATTACTGGTCAGGCTTATCAGAAAGACGGTCACTTCGAGCTGCTGCCTTTT
TCTTATCGCTTAGAGGAGCTGTTTGAGGAAGCGGGCCAAATTGCAGAAGCTGTTCGCGCTAAGCATGTAGGTACTGAACA
TGTGCTGCTGGCCATGCTATTTGACCGGGGGACCTTGGCTTCTCGTATCCTGGAATTTACCGGCTTTAACTACGAGGACA
AGGAGCAGGGGCCGAAAATCAGTGATTTGCGTAAGGTCTTGGAGCAGCGAGCTGGCTGGGGCAAGGAAGATATCAAGGCT
ATCCGCAGTCTGAATAAGGGAGTAATGGCTGCTAAGCAGACCATGGCTAATATGATGGGAATGCCGGCTTCTACCAGCGG
GGGGCTGGAAGATTACACTCGTGATCTGACGGAGCTGGCTAGAGATGGCCGATTGGAACCCGTCATTGGCCGTGATCAGG
AAATTTCACGGATAGTTCAGATTCTCAGTCGCAAGACCAAAAATAATCCAGTGCTGGTTGGAGATGCTGGGGTTGGTAAG
ACAGCTCTGGCTTTAGGTCTGGCCCAGCGTGTGGCAGCTGGTCAGGTTCCAGCTGAACTGGCCAAGATGCGGGTCTTGGA
GCTGGACTTGATGAATGTAGTCGCTGGCACTCGCTTTCGCGGAGATTTCGAGGAGCGGATGAACAACATCATCAATGACA
TTGAAGAAGATGGTCATGTCATTCTCTTCATCGATGAGCTGCATACTATCATGGGCTCTGGCAGCGGTATTGACTCGACC
TTGGATGCGGCCAATATCCTGAAACCGGCTCTGGCTCGCGGAACATTGCGGACAGTTGGTGCTACGACCCAGGAAGAGTA
CCAGAAACATATTGAAAAAGATGCTGCTCTCTCTCGGCGTTTTGCCAAGGTCAGCATAGAAGAGCCGAATGTGGCTGACA
GCATTGCTATTTTACAAGGTTTGAGAAAGAGTTATGAGGACCATCACAAGGTGCAGATCAGTGATCAGGCTATCGAGACA
GCGGTCAAATATGCCCATCGCTATCTGACCAGTAAGCACCTGCCAGACTCTGCCATTGATCTTTTGGATGAGGCCAGTGC
GACAGTACAGAATAGAGGACCGCAGAATTACGAGCAGTCGGATTTGACGCCAGTTGATCAGGCCTTGATGGTAGCGGATT
TCAAAAAAGTCTCGAAGTTGCTTAAGCAAGAGCAGCAACCCAAGCTTTATAAGCTGAAAGTGGAAGAAGGCGATGTCTTG
GCTACTCTTAGTGCTTTATCTGGTATTCCAGTGCAGAAGCTGACTCAGACAGATGCCAAGAAATACCTCAATTTGGAAAC
AGAACTGCATAAACGTGTTATTGGGCAGGACGAGGCGATTTCAGCTATCAGCCGAGCTATCCGACGAAACCAGTCTGGTA
TCCGCAGCAGTAAGCGGCCGATTGGCTCCTTTATGTTCCTAGGTCCGACAGGGGTCGGGAAGACAGAGCTAGCCAAGGCC
TTGGCCGAAAGTCTCTTTGATGATGAGTCTGCACTCATCCGCTTTGATATGAGTGAGTACATGGAGAAATTCGCGGCTAG
CCGCCTCAACGGAGCGCCTCCAGGCTATGTAGGCTATGAAGAGGGAGGGGAGCTGACGGAGAAGGTGCGCAACAGACCTT
ATTCTGTCCTGCTCTTTGACGAGGTAGAAAAGGCGCATCCAGATATTTTCAATGTTCTCCTGCAGGTCTTGGATGATGGT
CAGCTGACTGACAGCAAGGGCCGCAAGGTGGACTTCTCCAACACGATTATTATCATGACCAGCAATCTGGGGGCAACCAG
TTTGCGGGATGATAAGACGGTGGGCTTTGGGGCGCGTGACATTCGCTTGGACCATGCCAATATGGAAAAACGGATGCTGG
AAGAACTCAAGAAAGCATATAGACCAGAGTTTATCAACCGTATTGACGAGAAGGTAGTCTTCCACAGCTTATCTGCAGAA
GATATGCAGGAAGTGGTCAAGGTTATGGTCAAACCGCTCATTGCCAGTCTTGCTGAGAAGGGAATTGAGCTGAAGTTTCA
GTCTAGTGCACTTAAGCTGCTGGCTCAGGAAGGATACGATGTGGAAATGGGAGCACGGCCATTGCGCCGAACTCTGCAGA
CGCAGGTGGAGGACAAGCTGTCAGAGCTGCTCCTGACAGGAGATTTGGCTGCTGGCCAAACACTTAAGGTTGGTGTCAAG
GCTGGCCAGCTCAAGTTCGAAGTGGCTTAG

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(371-453)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(100-134)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-60)

AAA domain (Cdc48 subfamily) (AAA_2)

(539-710)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(717-797)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae TIGR4

77.531

100

0.776
  clpC Streptococcus pneumoniae Rx1

77.531

100

0.776
  clpC Streptococcus pneumoniae D39

77.531

100

0.776
  clpC Streptococcus mutans UA159

68.182

100

0.686
  clpC Streptococcus thermophilus LMG 18311

66.913

100

0.672
  clpC Streptococcus thermophilus LMD-9

66.79

100

0.671
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.363

100

0.514
  clpC Bacillus subtilis subsp. subtilis str. 168

45.318

99.011

0.449
  clpE Streptococcus pneumoniae TIGR4

46.094

79.11

0.365
  clpE Streptococcus pneumoniae Rx1

46.094

79.11

0.365
  clpE Streptococcus pneumoniae D39

46.094

79.11

0.365
  clpE Streptococcus pneumoniae R6

46.094

79.11

0.365
  clpE Streptococcus mutans UA159

47.65

76.267

0.363

Multiple sequence alignment