Detailed information NTG1116968

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EW031_RS14825
• Genome accession: NZ_LR130518
• Coordinates: 2786623..2787510 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BPH2986 isolate BPH2986
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2781623..2792510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW031_RS14790	-	2781642..2781734 (+)	93	WP_010956583.1	hypothetical protein	-
EW031_RS14795	-	2781842..2782339 (-)	498	WP_001065268.1	glutathione peroxidase	-
EW031_RS14800	-	2782349..2782609 (-)	261	WP_001789910.1	hypothetical protein	-
EW031_RS14810	-	2782991..2783104 (-)	114	WP_001791776.1	hypothetical protein	-
EW031_RS14815	-	2783763..2785763 (-)	2001	WP_000776751.1	ABC transporter permease	-
EW031_RS14820	-	2785760..2786515 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EW031_RS14825	braS	2786623..2787510 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EW031_RS14830	braR	2787521..2788186 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EW031_RS14835	-	2788212..2788412 (-)	201	WP_000604728.1	hypothetical protein	-
EW031_RS14840	-	2788610..2790034 (+)	1425	WP_000953744.1	alkaline phosphatase	-
EW031_RS15820	-	2790094..2790195 (-)	102	WP_000731972.1	SE2200 family small protein	-
EW031_RS14850	-	2790317..2790772 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EW031_RS14855	-	2791017..2791778 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1116968 EW031_RS14825 WP_000143419.1 2786623..2787510(-) (braS) [Staphylococcus aureus strain BPH2986 isolate BPH2986]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1116968 EW031_RS14825 WP_000143419.1 2786623..2787510(-) (braS) [Staphylococcus aureus strain BPH2986 isolate BPH2986]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997