Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EW033_RS11485 Genome accession   NZ_LR130515
Coordinates   2179428..2180144 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain BPH2947 isolate BPH2947     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2174428..2185144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW033_RS11455 - 2174647..2175273 (+) 627 WP_000522384.1 nitroreductase family protein -
  EW033_RS11460 - 2175634..2176419 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  EW033_RS16675 hld 2177016..2177096 (-) 81 WP_000046022.1 delta-hemolysin -
  EW033_RS11470 agrB 2177386..2177955 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  EW033_RS11475 agrD 2177952..2178092 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  EW033_RS11480 agrC 2178117..2179409 (+) 1293 WP_014532426.1 quorum-sensing sensor histidine kinase AgrC -
  EW033_RS11485 agrA 2179428..2180144 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  EW033_RS11490 - 2180216..2180323 (+) 108 WP_001790167.1 hypothetical protein -
  EW033_RS11495 - 2180511..2181470 (-) 960 WP_001253313.1 carbohydrate kinase family protein -
  EW033_RS11500 - 2181467..2182951 (-) 1485 WP_000141417.1 sucrose-6-phosphate hydrolase -
  EW033_RS11505 - 2183100..2184050 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1116921 EW033_RS11485 WP_000688492.1 2179428..2180144(+) (agrA) [Staphylococcus aureus strain BPH2947 isolate BPH2947]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1116921 EW033_RS11485 WP_000688492.1 2179428..2180144(+) (agrA) [Staphylococcus aureus strain BPH2947 isolate BPH2947]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment