Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EW029_RS14070 Genome accession   NZ_LR130513
Coordinates   2723251..2723916 (-) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain BPH2900 isolate BPH2900     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2718251..2728916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW029_RS14050 - 2718716..2718829 (-) 114 WP_072384844.1 hypothetical protein -
  EW029_RS14055 - 2719493..2721493 (-) 2001 WP_000776746.1 ABC transporter permease -
  EW029_RS14060 - 2721490..2722245 (-) 756 WP_001670202.1 ABC transporter ATP-binding protein -
  EW029_RS14065 braS 2722353..2723240 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  EW029_RS14070 braR 2723251..2723916 (-) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  EW029_RS14075 - 2723942..2724142 (-) 201 WP_000604723.1 hypothetical protein -
  EW029_RS14080 - 2724340..2725764 (+) 1425 WP_000953731.1 alkaline phosphatase -
  EW029_RS14805 - 2725824..2725925 (-) 102 WP_000731972.1 SE2200 family small protein -
  EW029_RS14090 - 2726047..2726502 (-) 456 WP_000106184.1 MarR family winged helix-turn-helix transcriptional regulator -
  EW029_RS14095 - 2726748..2727509 (-) 762 WP_000323451.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=1116883 EW029_RS14070 WP_000697883.1 2723251..2723916(-) (braR) [Staphylococcus aureus strain BPH2900 isolate BPH2900]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1116883 EW029_RS14070 WP_000697883.1 2723251..2723916(-) (braR) [Staphylococcus aureus strain BPH2900 isolate BPH2900]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACGGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGACAATACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATTATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment