Detailed information NTG1116839

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EW030_RS13645
• Genome accession: NZ_LR130511
• Coordinates: 2631167..2632054 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BPH2819 isolate BPH2819
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2626167..2637054

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW030_RS13610	-	2626186..2626278 (+)	93	WP_010956583.1	hypothetical protein	-
EW030_RS13615	-	2626386..2626883 (-)	498	WP_001065268.1	glutathione peroxidase	-
EW030_RS13620	-	2626893..2627153 (-)	261	WP_001791974.1	hypothetical protein	-
EW030_RS13630	-	2627535..2627648 (-)	114	Protein_2533	hypothetical protein	-
EW030_RS13635	-	2628307..2630307 (-)	2001	WP_000776751.1	ABC transporter permease	-
EW030_RS13640	-	2630304..2631059 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EW030_RS13645	braS	2631167..2632054 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EW030_RS13650	braR	2632065..2632730 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EW030_RS13655	-	2632756..2632956 (-)	201	WP_000604730.1	hypothetical protein	-
EW030_RS13660	-	2633154..2634578 (+)	1425	WP_000953755.1	alkaline phosphatase	-
EW030_RS14605	-	2634638..2634739 (-)	102	WP_000731976.1	SE2200 family small protein	-
EW030_RS13670	-	2634861..2635316 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EW030_RS13675	-	2635561..2636322 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1116839 EW030_RS13645 WP_000143425.1 2631167..2632054(-) (braS) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1116839 EW030_RS13645 WP_000143425.1 2631167..2632054(-) (braS) [Staphylococcus aureus strain BPH2819 isolate BPH2819]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1