Detailed information NTG1116797

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EW032_RS13470
• Genome accession: NZ_LR130509
• Coordinates: 2619736..2620623 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain BPH2760 isolate BPH2760
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2614736..2625623

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW032_RS13435	-	2614755..2614847 (+)	93	WP_010956583.1	hypothetical protein	-
EW032_RS13440	-	2614955..2615452 (-)	498	WP_001065268.1	glutathione peroxidase	-
EW032_RS13445	-	2615462..2615722 (-)	261	WP_001791974.1	hypothetical protein	-
EW032_RS13455	-	2616104..2616217 (-)	114	Protein_2491	hypothetical protein	-
EW032_RS13460	-	2616876..2618876 (-)	2001	WP_000776740.1	ABC transporter permease	-
EW032_RS13465	-	2618873..2619628 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EW032_RS13470	braS	2619736..2620623 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EW032_RS13475	braR	2620634..2621299 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EW032_RS13480	-	2621325..2621525 (-)	201	WP_000604727.1	hypothetical protein	-
EW032_RS13485	-	2621723..2623147 (+)	1425	WP_000953748.1	alkaline phosphatase	-
EW032_RS14365	-	2623207..2623308 (-)	102	WP_000731972.1	SE2200 family small protein	-
EW032_RS13495	-	2623430..2623885 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EW032_RS13500	-	2624130..2624891 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1116797 EW032_RS13470 WP_000143417.1 2619736..2620623(-) (braS) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1116797 EW032_RS13470 WP_000143417.1 2619736..2620623(-) (braS) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99