Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EW032_RS10205 Genome accession   NZ_LR130509
Coordinates   2000505..2001221 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain BPH2760 isolate BPH2760     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1995505..2006221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW032_RS10175 - 1995721..1996347 (+) 627 WP_000522384.1 nitroreductase family protein -
  EW032_RS10180 - 1996708..1997493 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  EW032_RS14350 hld 1998092..1998172 (-) 81 WP_000046023.1 delta-hemolysin -
  EW032_RS10190 - 1998462..1999025 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  EW032_RS10195 agrD 1999029..1999169 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  EW032_RS10200 agrC 1999194..2000486 (+) 1293 WP_000387803.1 quorum-sensing sensor histidine kinase AgrC -
  EW032_RS10205 agrA 2000505..2001221 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  EW032_RS10210 - 2001293..2001402 (+) 110 Protein_1886 hypothetical protein -
  EW032_RS10215 - 2001590..2002549 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  EW032_RS10220 - 2002546..2004030 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  EW032_RS10225 - 2004179..2005129 (-) 951 WP_000790327.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1116793 EW032_RS10205 WP_000688492.1 2000505..2001221(+) (agrA) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1116793 EW032_RS10205 WP_000688492.1 2000505..2001221(+) (agrA) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment