Detailed information    

insolico Bioinformatically predicted

Overview

Name   comS   Type   Regulator
Locus tag   EW023_RS10010 Genome accession   NZ_LR130239
Coordinates   53864..53962 (+) Length   32 a.a.
NCBI ID   WP_206733287.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain PS003 isolate PS003     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48864..58962
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW023_RS00320 purK 48937..50010 (+) 1074 WP_023611330.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  EW023_RS00325 - 50012..51430 (+) 1419 WP_023612101.1 hypothetical protein -
  EW023_RS00330 purB 51450..52742 (+) 1293 WP_023612104.1 adenylosuccinate lyase -
  EW023_RS00335 comR 52873..53784 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  EW023_RS10010 comS 53864..53962 (+) 99 WP_206733287.1 quorum-sensing system DWW-type pheromone Regulator
  EW023_RS00340 ruvB 54009..55007 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  EW023_RS00345 - 55145..55582 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  EW023_RS00350 - 55605..56006 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  EW023_RS00355 - 56003..57778 (+) 1776 WP_129758815.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 32 a.a.        Molecular weight: 3980.77 Da        Isoelectric Point: 10.0437

>NTDB_id=1116704 EW023_RS10010 WP_206733287.1 53864..53962(+) (comS) [Streptococcus pyogenes strain PS003 isolate PS003]
MHVKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 99 bp        

>NTDB_id=1116704 EW023_RS10010 WP_206733287.1 53864..53962(+) (comS) [Streptococcus pyogenes strain PS003 isolate PS003]
ATCCATGTTAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGT
TGACTGGTGGCGATTATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

96.667

93.75

0.906
  comS Streptococcus pyogenes MGAS315

40

93.75

0.375

Multiple sequence alignment