Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   EW024_RS08785 Genome accession   NZ_LR130237
Coordinates   1736650..1737363 (+) Length   237 a.a.
NCBI ID   WP_002982243.1    Uniprot ID   A0A9X5LXW4
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1731650..1742363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS08775 treC 1732719..1734347 (-) 1629 WP_011529089.1 alpha,alpha-phosphotrehalase -
  EW024_RS08780 treP 1734415..1736439 (-) 2025 WP_011529090.1 PTS system trehalose-specific EIIBC component -
  EW024_RS08785 treR 1736650..1737363 (+) 714 WP_002982243.1 trehalose operon repressor Regulator
  EW024_RS08795 - 1737642..1737980 (-) 339 WP_011529091.1 winged helix-turn-helix transcriptional regulator -
  EW024_RS08800 - 1738166..1739014 (+) 849 Protein_1621 VOC family protein -
  EW024_RS08805 yaaA 1739056..1739787 (+) 732 WP_011529093.1 peroxide stress protein YaaA -
  EW024_RS08810 nrdG 1739961..1740575 (-) 615 WP_021299115.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  EW024_RS08815 - 1740590..1741084 (-) 495 WP_011055085.1 GNAT family N-acetyltransferase -
  EW024_RS08820 - 1741093..1742028 (-) 936 WP_021299109.1 Gfo/Idh/MocA family protein -
  EW024_RS09305 - 1742057..1742203 (-) 147 WP_011106921.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27592.78 Da        Isoelectric Point: 9.6226

>NTDB_id=1116586 EW024_RS08785 WP_002982243.1 1736650..1737363(+) (treR) [Streptococcus pyogenes strain SP444 isolate SP444]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=1116586 EW024_RS08785 WP_002982243.1 1736650..1737363(+) (treR) [Streptococcus pyogenes strain SP444 isolate SP444]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTTTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679

Multiple sequence alignment