Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   EW024_RS02470 Genome accession   NZ_LR130237
Coordinates   446917..447726 (+) Length   269 a.a.
NCBI ID   WP_002985641.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 441917..452726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS02450 - 442359..443606 (+) 1248 WP_011528374.1 AMP-binding protein -
  EW024_RS02455 - 443662..444696 (+) 1035 WP_011528375.1 DUF3114 domain-containing protein -
  EW024_RS02460 vicR 444858..445568 (+) 711 WP_002985645.1 response regulator YycF Regulator
  EW024_RS02465 vicK 445561..446913 (+) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EW024_RS02470 vicX 446917..447726 (+) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  EW024_RS02475 rnc 448169..448861 (+) 693 WP_002990670.1 ribonuclease III -
  EW024_RS02480 smc 448862..452401 (+) 3540 WP_011528376.1 chromosome segregation protein SMC -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 30095.20 Da        Isoelectric Point: 5.5314

>NTDB_id=1116562 EW024_RS02470 WP_002985641.1 446917..447726(+) (vicX) [Streptococcus pyogenes strain SP444 isolate SP444]
MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLLAEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLD
IYANEKTWQLMDECNMLGKLDASQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKKIYLGHLSKENNIKELAHMTMVN
QLAMADLAVGTDFTVHDTSPDTACPLTDI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1116562 EW024_RS02470 WP_002985641.1 446917..447726(+) (vicX) [Streptococcus pyogenes strain SP444 isolate SP444]
ATGAATGAGAGTGGTTTTAAATATAGTATTTTAGCATCTGGGTCCACAGGAAATTGTTTTTATTTAGAAACACCTAAAAA
ACGCTTATTGATTGATGCAGGGCTTACTGGTAAGAAAATTACCAGTCTTCTTGCTGAAATTGACCGCAAACCTGAGGATT
TGGATGCTATTTTGATTACCCATGAGCACTCTGACCATATTAAGGGTGTAGGCGTTATGGCCCGCAAATACCATTTGGAT
ATCTATGCTAATGAAAAAACATGGCAGCTGATGGATGAGTGCAATATGCTAGGTAAGCTTGATGCCTCACAAAAACATAT
TTTCCAAAGGGATAAAGTTTTGACCTTTGGAGATGTTGATATCGAAAGTTTTGGAGTCAGCCATGACGCTATTGATCCTC
AATTTTATCGGATTATGAAAGATAATAAGTCTTTTGTGATGTTGACAGATACAGGATATGTCAGTGATAGGATGACAGGT
ATTATTGAAAATGCAGATGGCTACTTGATTGAATCCAATCATGATATTGAAATTTTGAGATCAGGCTCTTATCCTTGGAG
CTTGAAGCAGCGTATTTTATCTGATTTAGGACATTTATCAAATGAAGATGGAGCGGGAGCCATGATTAGAAGCCTGGGGT
ACAATACCAAAAAAATATACCTAGGTCATCTGAGTAAAGAAAATAACATCAAAGAGTTAGCGCATATGACGATGGTCAAT
CAACTGGCTATGGCAGATTTAGCAGTAGGTACAGACTTTACGGTCCATGATACCTCTCCAGATACTGCTTGTCCATTAAC
TGATATTTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

75.836

100

0.758

Multiple sequence alignment