Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   EW021_RS09750 Genome accession   NZ_LR130236
Coordinates   48087..48182 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 5448 isolate 5448     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 43087..53182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW021_RS00255 - 44007..45650 (+) 1644 WP_010921779.1 AIPR family protein -
  EW021_RS00260 purB 45668..46960 (+) 1293 WP_010921780.1 adenylosuccinate lyase -
  EW021_RS00265 comR 47092..48003 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  EW021_RS09750 comS 48087..48182 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  EW021_RS00270 ruvB 48229..49227 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  EW021_RS00275 - 49365..49802 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  EW021_RS00280 - 49825..50226 (+) 402 WP_010921781.1 MORN repeat-containing protein -
  EW021_RS00285 - 50223..51998 (+) 1776 WP_010921782.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=1116536 EW021_RS09750 WP_198462994.1 48087..48182(+) (comS) [Streptococcus pyogenes strain 5448 isolate 5448]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=1116536 EW021_RS09750 WP_198462994.1 48087..48182(+) (comS) [Streptococcus pyogenes strain 5448 isolate 5448]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452


Multiple sequence alignment