Detailed information NTG1116451

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EQB47_RS09605
• Genome accession: NZ_LR129844
• Coordinates: 1756586..1757623 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727279.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 180-15 isolate 180-15
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1751586..1762623

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB47_RS09580	-	1752325..1753656 (-)	1332	WP_000390039.1	hemolysin family protein	-
EQB47_RS09585	endA	1753947..1754771 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
EQB47_RS09590	-	1754810..1754998 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
EQB47_RS09595	murA	1754991..1756274 (-)	1284	WP_000358034.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EQB47_RS09600	-	1756298..1756528 (-)	231	WP_001809307.1	DUF1146 family protein	-
EQB47_RS09605	sepM	1756586..1757623 (-)	1038	WP_000727279.1	SepM family pheromone-processing serine protease	Regulator
EQB47_RS09610	coaD	1757607..1758095 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
EQB47_RS09615	rsmD	1758085..1758624 (-)	540	WP_000706951.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EQB47_RS09620	asnA	1758689..1759681 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
EQB47_RS09630	-	1759793..1760476 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
EQB47_RS09635	-	1760532..1761272 (-)	741	WP_000152680.1	TrmH family RNA methyltransferase	-
EQB47_RS09640	-	1761306..1761584 (+)	279	WP_054392911.1	acylphosphatase	-
EQB47_RS09645	yidC	1761662..1762588 (+)	927	WP_000835949.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37565.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=1116451 EQB47_RS09605 WP_000727279.1 1756586..1757623(-) (sepM) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1116451 EQB47_RS09605 WP_000727279.1 1756586..1757623(-) (sepM) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-298)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588