Detailed information NTG1116372

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EQB46_RS09595
• Genome accession: NZ_LR129843
• Coordinates: 1756732..1757769 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727279.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 180-2 isolate 180-2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1751732..1762769

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB46_RS09570	-	1752471..1753802 (-)	1332	WP_000390039.1	hemolysin family protein	-
EQB46_RS09575	endA	1754093..1754917 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
EQB46_RS09580	-	1754956..1755144 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
EQB46_RS09585	murA	1755137..1756420 (-)	1284	WP_000358034.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EQB46_RS09590	-	1756444..1756674 (-)	231	WP_001809307.1	DUF1146 family protein	-
EQB46_RS09595	sepM	1756732..1757769 (-)	1038	WP_000727279.1	SepM family pheromone-processing serine protease	Regulator
EQB46_RS09600	coaD	1757753..1758241 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
EQB46_RS09605	rsmD	1758231..1758770 (-)	540	WP_000706951.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EQB46_RS09610	asnA	1758835..1759827 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
EQB46_RS09620	-	1759939..1760622 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
EQB46_RS09625	-	1760678..1761418 (-)	741	WP_000152680.1	TrmH family RNA methyltransferase	-
EQB46_RS09630	-	1761452..1761730 (+)	279	WP_001174613.1	acylphosphatase	-
EQB46_RS09635	yidC	1761808..1762734 (+)	927	WP_000835949.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37565.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=1116372 EQB46_RS09595 WP_000727279.1 1756732..1757769(-) (sepM) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1116372 EQB46_RS09595 WP_000727279.1 1756732..1757769(-) (sepM) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-298)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588